KHK

Description		ketohexokinase
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GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Nucleotide Binding Ketohexokinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Identical Protein Binding Protein Homodimerization Activity Fructose Binding
	Biological Process	Fructose Metabolic Process Response To Sucrose Response To Glucose Response To Fructose Response To Zinc Ion Response To Insulin Carbohydrate Phosphorylation Regulation Of Glycogen Metabolic Process
Pathways		Essential fructosuria Fructose catabolism
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Self-reported risk-taking behaviour ( 30181555) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		4 interacting genes: APPBP2 GLP1R LHX2 LHX9
Entrez ID		3795
HPRD ID		11774
Ensembl ID		ENSG00000138030
Uniprot IDs		A0A140VJM6 C9JDL1 P50053
PDB IDs		2HLZ 2HQQ 2HW1 3B3L 3NBV 3NBW 3NC2 3NC9 3NCA 3Q92 3QA2 3QAI 3RO4 5WBM 5WBO 5WBP 5WBQ 5WBR 5WBZ 6UL7 6W0N 6W0W 6W0X 6W0Y 6W0Z 8OME 8OMF 8OMJ 8OMK 8UG1 8UG3 9FHD 9FHE
Enriched GO Terms of Interacting Partners?		Glucagon-like Peptide 1 Receptor Activity Gonad Morphogenesis Dorsal Spinal Cord Interneuron Anterior Axon Guidance Spinal Cord Interneuron Axon Guidance Glucagon Receptor Activity Interneuron Axon Guidance Neuron Projection Guidance Axon Guidance Response To Psychosocial Stress Maintenance Of Epithelial Cell Apical/basal Polarity Telencephalon Regionalization Anterior/posterior Axon Guidance Post-translational Protein Targeting To Membrane, Translocation Cellular Response To Glucagon Stimulus Neuron Differentiation RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Activation Of Adenylate Cyclase Activity Maintenance Of Cell Polarity Positive Regulation Of Lyase Activity Positive Regulation Of Adenylate Cyclase Activity Response To Glucagon Sequence-specific DNA Binding Neuron Projection Development Cul2-RING Ubiquitin Ligase Complex Positive Regulation Of Cyclase Activity Intracellular Protein Transport Olfactory Bulb Development Female Gonad Development
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