SLC26A5

Description		solute carrier family 26 member 5
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GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Lateral Plasma Membrane Lateral Wall Of Outer Hair Cell
	Molecular Function	Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Oxalate Transmembrane Transporter Activity Spectrin Binding Identical Protein Binding Protein Homodimerization Activity Chloride:bicarbonate Antiporter Activity
	Biological Process	Response To Ischemia Chloride Transport Sensory Perception Of Sound Regulation Of Cell Shape Response To Xenobiotic Stimulus Response To Salicylic Acid Response To Auditory Stimulus Bicarbonate Transport Fructose Transmembrane Transport Oxalate Transport Monoatomic Ion Transmembrane Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Response To Potassium Ion Regulation Of Membrane Potential Positive Regulation Of Cell Size Transmembrane Transport Cochlea Development Response To Thyroid Hormone Monoatomic Anion Transmembrane Transport Response To Salt Sulfate Transmembrane Transport Chloride Transmembrane Transport Positive Regulation Of Cell Motility
Pathways		Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases		Deafness, autosomal recessive
GWAS		Age-related hearing impairment ( 34108613) Femur bone mineral density x serum urate levels interaction ( 34046847) Morning person ( 30696823)
Interacting Genes		1 interacting genes: UBE2J1
Entrez ID		375611
HPRD ID		09224
Ensembl ID		ENSG00000170615
Uniprot IDs		P58743
PDB IDs		7LGU 7LGW 7LH2 7LH3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Retrograde Protein Transport, ER To Cytosol Hrd1p Ubiquitin Ligase Complex Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein N-linked Glycosylation Via Asparagine Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Macrophage Cytokine Production Negative Regulation Of Intracellular Protein Transport Ubiquitin Conjugating Enzyme Activity Negative Regulation Of Intracellular Transport Protein N-linked Glycosylation ERAD Pathway Spermatid Development Negative Regulation Of Protein Transport Regulation Of Cytokine Production Involved In Immune Response Regulation Of Intracellular Protein Transport Negative Regulation Of Establishment Of Protein Localization
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