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IRF6
Gene Name
interferon regulatory factor 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Regulatory Region DNA Binding
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Biological Process
Transcription, DNA-templated
Cell Cycle Arrest
Negative Regulation Of Cell Proliferation
Cytokine-mediated Signaling Pathway
Keratinocyte Differentiation
Keratinocyte Proliferation
Positive Regulation Of Transcription, DNA-templated
Cell Development
Interferon-gamma-mediated Signaling Pathway
Type I Interferon Signaling Pathway
Mammary Gland Epithelial Cell Differentiation
Pathways
Interferon gamma signaling
Interferon Signaling
Cytokine Signaling in Immune system
Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Cleft lip (
20436469
)
Orofacial clefts (
19270707
22863734
)
Protein-protein Interactions
5 interactors:
IRF8
LBP
RFX3
TLX2
ZBTB3
Entrez ID
3664
HPRD ID
06227
Ensembl ID
ENSG00000117595
Uniprot IDs
G0Z349
O14896
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Growth Of Symbiont In Host
Cellular Response To Lipopolysaccharide
Positive Regulation Of Respiratory Burst Involved In Inflammatory Response
Leukocyte Chemotaxis Involved In Inflammatory Response
Type B Pancreatic Cell Maturation
Lipopolysaccharide Transport
Transcription, DNA-templated
Cellular Response To Molecule Of Bacterial Origin
RNA Biosynthetic Process
Defense Response To Bacterium
Cilium-dependent Cell Motility
Positive Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Growth
Phagocytosis
Glandular Epithelial Cell Maturation
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
RNA Metabolic Process
Positive Regulation Of Respiratory Burst
Response To Lipopolysaccharide
Negative Regulation Of Dendrite Morphogenesis
Response To Molecule Of Bacterial Origin
Gene Expression
Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry
Cilium Or Flagellum-dependent Cell Motility
Positive Regulation Of Cytokine Production
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Opsonization
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Respiratory Burst
Macrophage Activation Involved In Immune Response
Positive Regulation Of Macrophage Activation
Macromolecule Biosynthetic Process
Positive Regulation Of Toll-like Receptor Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of DNA-templated Transcription, Initiation
Enteric Nervous System Development
Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process
Cellular Response To Lipoteichoic Acid
Detection Of Molecule Of Bacterial Origin
Cellular Response To Lipid
Regulation Of Metabolic Process
Negative Regulation Of Dendrite Development
Type B Pancreatic Cell Development
Leukocyte Migration Involved In Inflammatory Response
Regulation Of DNA-templated Transcription, Initiation
Response To Bacterium
Defense Response To Protozoan
Regulation Of Tumor Necrosis Factor Biosynthetic Process
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cd68
conceptus
coordinately
dialogue
enjsrv
ensures
env
estrous
ewes
exosomal
exosomes
flushings
hsc70
ifnt
interleukins
irak1
irf7
jaagsiekte
liberated
oftlr
otr1
ovine
plasmacytoid
proliferated
retroviruses
ruminants
tlr
trophectoderm
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