INPP4A

Gene Name		inositol polyphosphate-4-phosphatase, type I, 107kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Phosphatidylinositol-3,4-bisphosphate 4-phosphatase Activity Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Activity
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Dephosphorylation Phosphatidylinositol-3-phosphate Biosynthetic Process Inositol Phosphate Metabolic Process Small Molecule Metabolic Process
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the early endosome membrane Synthesis of IP2, IP, and Ins in the cytosol Metabolism of lipids and lipoproteins Phospholipid metabolism Inositol phosphate metabolism PI Metabolism
Drugs
Diseases
GWAS		Bipolar disorder (mood-incongruent) ( 23092984)
Protein-protein Interactions		3 interactors: CAPN1 PIK3R1 SMAD1
Entrez ID		3631
HPRD ID		02949
Ensembl ID		ENSG00000040933
Uniprot IDs		Q96PE3
PDB IDs
Enriched GO Terms of Interacting Partners?		NFAT Protein Import Into Nucleus Transcription Factor Import Into Nucleus Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Primary MiRNA Processing Osteoblast Fate Commitment Posttranscriptional Regulation Of Gene Expression SMAD Protein Complex Assembly Receptor Catabolic Process Cellular Response To Growth Factor Stimulus Mesodermal Cell Fate Commitment Wound Healing Response To Growth Factor Insulin-like Growth Factor Receptor Signaling Pathway Cardiac Muscle Cell Proliferation Response To Wounding Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Growth Hormone Receptor Signaling Pathway Mesodermal Cell Differentiation Positive Regulation Of Protein Localization To Plasma Membrane Cellular Response To Growth Hormone Stimulus Negative Regulation Of Osteoclast Differentiation Response To Organonitrogen Compound Cell Fate Commitment Involved In Formation Of Primary Germ Layer Cardiac Muscle Tissue Growth Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Dendrite Morphogenesis Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of RNA Splicing Gene Silencing By MiRNA Negative Regulation Of Cell-matrix Adhesion Cellular Response To DsRNA Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Cartilage Development Negative Regulation Of Cell Death Posttranscriptional Gene Silencing Response To Growth Hormone Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Glucose Import Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Glucose Transport Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Myeloid Leukocyte Differentiation
Tagcloud ?		7a abcc2 carboplatin chemotoxicity dspr fecundity founder gemcitabine gpx4 inbred intercross interindividual mitomycin msh2 multiparent nalcn nonsynonymous ortholog orthologs posteriori priori qtl revolutionize rrm2 rrm2b segregating singly solute transposable