FOXK2

Gene Name		forkhead box K2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: IL2 IRF2
Entrez ID		3607
HPRD ID		00982
Ensembl ID		ENSG00000141568
Uniprot IDs		Q01167
PDB IDs		1JXS 2C6Y
Enriched GO Terms of Interacting Partners?		Regulation Of T Cell Homeostatic Proliferation Positive Regulation Of Regulatory T Cell Differentiation Positive Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of Immunoglobulin Secretion Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of Interleukin-17 Production Negative Regulation Of B Cell Apoptotic Process Regulation Of Immunoglobulin Secretion Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Regulation Of B Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Heart Contraction Positive Regulation Of Activated T Cell Proliferation Positive Regulation Of Isotype Switching Positive Regulation Of Dendritic Spine Development Positive Regulation Of Tissue Remodeling Regulation Of Isotype Switching Positive Regulation Of Immunoglobulin Mediated Immune Response Immune Response Regulation Of Activated T Cell Proliferation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Immunoglobulin Production Positive Regulation Of B Cell Proliferation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Dendritic Spine Development Positive Regulation Of Macromolecule Biosynthetic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Interferon-gamma Production Negative Regulation Of Leukocyte Apoptotic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of B Cell Proliferation Positive Regulation Of Dendrite Development Natural Killer Cell Activation Positive Regulation Of JAK-STAT Cascade Regulation Of Lymphocyte Apoptotic Process Regulation Of Tissue Remodeling Regulation Of DNA Recombination Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Positive Regulation Of B Cell Activation Negative Regulation Of Leukocyte Proliferation Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Differentiation Regulation Of Interferon-gamma Production Regulation Of JAK-STAT Cascade Positive Regulation Of Lymphocyte Differentiation Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		attenuation bcl2 brdu compensating dramatic emphasized forkhead gadd45alpha gadd45gamma gadd45s inc indicative iodide knockdown noxa p70s6k partly periodicals physiol potentiated propidium puma rapamycin requirement synergistically tgfbeta ubiquitously upregulating wiley