SHROOM2

Description		shroom family member 2
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Apical Plasma Membrane Cortical Actin Cytoskeleton Apical Junction Complex Extracellular Exosome Anchoring Junction
	Molecular Function	Actin Binding Protein Binding Beta-catenin Binding Ligand-gated Sodium Channel Activity Actin Filament Binding
	Biological Process	Cell Morphogenesis Lens Morphogenesis In Camera-type Eye Actin Filament Organization Brain Development Eye Pigment Granule Organization Cell Migration Establishment Of Melanosome Localization Melanosome Organization Sodium Ion Transmembrane Transport Camera-type Eye Development Cellular Pigment Accumulation Ear Development Apical Protein Localization Camera-type Eye Morphogenesis Actin Filament Bundle Assembly
Pathways
Drugs
Diseases
GWAS		Colorectal cancer ( 22634755) Prostate cancer ( 23535732)
Interacting Genes		4 interacting genes: ACE2 RPS6KA1 TTC3 YWHAG
Entrez ID		357
HPRD ID		02113
Ensembl ID		ENSG00000146950
Uniprot IDs		B7Z682 F5H3B6 Q13796
PDB IDs		5F4Y 5F5P
Enriched GO Terms of Interacting Partners?		Regulation Of TOR Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Intracellular Signal Transduction TOR Signaling TORC1 Signaling Positive Regulation Of L-proline Import Across Plasma Membrane Angiotensin-mediated Drinking Behavior Peptidyl-dipeptidase Activity Protein Kinase C Inhibitor Activity Entry Receptor-mediated Virion Attachment To Host Cell Protein Metabolic Process Viral Translation Viral Life Cycle Hepatocyte Proliferation Positive Regulation Of Hepatic Stellate Cell Activation Ribosomal Protein S6 Kinase Activity Protein Polyubiquitination Proteolysis Receptor-mediated Virion Attachment To Host Cell Tryptophan Transport Positive Regulation Of Gap Junction Assembly Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell Phosphorylation-dependent Protein Binding Aromatic Amino Acid Transport Transporter Activator Activity Positive Regulation Of Cardiac Muscle Contraction Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Regulation Of Gap Junction Assembly Virion Attachment To Host Cell Drinking Behavior Adhesion Of Symbiont To Host Cell Receptor-mediated Endocytosis Of Virus By Host Cell Angiotensin Maturation Protein Modification Process Positive Regulation Of Cell Activation Negative Regulation Of Immune Response To Tumor Cell Adhesion Of Symbiont To Host Positive Regulation Of Striated Muscle Contraction Endocytosis Involved In Viral Entry Into Host Cell Positive Regulation Of Multicellular Organismal Process Regulation Of Translation Regulation Of T Cell Mediated Immune Response To Tumor Cell Insulin-like Growth Factor Receptor Binding Positive Regulation Of Immune Response To Tumor Cell Regulation Of Translation In Response To Stress Positive Regulation Of Amino Acid Transport
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