APRT

Gene Name		adenine phosphoribosyltransferase
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Adenine Binding Adenine Phosphoribosyltransferase Activity AMP Binding
	Biological Process	Purine Nucleobase Metabolic Process Adenine Salvage Lactation Grooming Behavior Cellular Response To Insulin Stimulus Purine-containing Compound Salvage AMP Salvage Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Purine metabolism Metabolism of nucleotides Purine salvage
Drugs		Adenine Alpha-Phosphoribosylpyrophosphoric Acid 9-Deazaadenine Citric Acid
Diseases
GWAS
Protein-protein Interactions		3 interactors: APP IKBKG MLH1
Entrez ID		353
HPRD ID		00029
Ensembl ID		ENSG00000198931
Uniprot IDs		P07741
PDB IDs		1OPU 1ORE 1ZN7 1ZN8 1ZN9
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway MRNA 3'-end Processing RNA 3'-end Processing Apoptotic Process Programmed Cell Death Cell Death Death Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Immune Response Intracellular Receptor Signaling Pathway Negative Regulation Of Mitotic Recombination Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Establishment Of Organelle Localization Collateral Sprouting Axon Midline Choice Point Recognition Establishment Of Localization In Cell Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Immune System Process Axon Choice Point Recognition Organelle Localization MRNA Processing Spindle Midzone Assembly Cellular Localization Neuron Remodeling Resolution Of Meiotic Recombination Intermediates MRNA Metabolic Process RNA Processing Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Cellular Copper Ion Homeostasis Cell Activation RNA Metabolic Process Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Copper Ion Homeostasis Suckling Behavior Regulation Of Protein Kinase Activity Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Isotype Switching Microtubule-based Process Response To Stress Gene Expression Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Tagcloud ?		62b11 alleles artificial behave breakpoints c1 capped chromosomes cytological deficiencies deleted lambda map maps melanogaster mu2 mutator phage positions potentiates presumptive protected recovered selectable spanning stocks subcloned subclones undiscovered