IGHA1

Description		immunoglobulin heavy constant alpha 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Immunoglobulin Complex Immunoglobulin Complex, Circulating Extracellular Exosome IgG Immunoglobulin Complex IgA Immunoglobulin Complex Monomeric IgA Immunoglobulin Complex Secretory IgA Immunoglobulin Complex Secretory Dimeric IgA Immunoglobulin Complex Blood Microparticle
	Molecular Function	Antigen Binding Immunoglobulin Receptor Binding
	Biological Process	Adaptive Immune Response Immune System Process Glomerular Filtration Immune Response Complement Activation, Classical Pathway Antibacterial Humoral Response B Cell Receptor Signaling Pathway Positive Regulation Of Respiratory Burst
Pathways
Drugs
Diseases
GWAS		Composite immunoglobulin trait (IgA/IgG) ( 28628107) Composite immunoglobulin trait (IgA/IgM) ( 28628107)
Interacting Genes		3 interacting genes: FYN LYN RNF115
Entrez ID		3493
HPRD ID
Ensembl ID		ENSG00000211895
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Innate Immune Response-activating Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of Innate Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Lectin Immune Response-regulating Cell Surface Receptor Signaling Pathway Activation Of Innate Immune Response Ephrin Receptor Binding Immune Response-activating Signaling Pathway Negative Regulation Of Inflammatory Response To Antigenic Stimulus Fc-gamma Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Activation Of Immune Response Regulation Of Innate Immune Response T Cell Costimulation Positive Regulation Of Defense Response Non-membrane Spanning Protein Tyrosine Kinase Activity Toll-like Receptor 4 Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Negative Regulation Of Immune System Process Cell Surface Pattern Recognition Receptor Signaling Pathway Fc Receptor Signaling Pathway Scaffold Protein Binding Positive Regulation Of Immune Response Positive Regulation Of Protein Localization To Membrane Regulation Of Defense Response Response To Amino Acid Lymphocyte Proliferation Mononuclear Cell Proliferation Regulation Of Immune Response Cellular Response To Glycine Response To Singlet Oxygen Protein Tyrosine Kinase Activity Transmembrane Transporter Binding Leukocyte Proliferation Positive Regulation Of Immune System Process Regulation Of Calcium Ion Transmembrane Transport Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Neuron Projection Development Pattern Recognition Receptor Signaling Pathway Regulation Of Protein Localization To Membrane Negative Regulation Of Inflammatory Response Response To Glycine Positive Regulation Of Oligodendrocyte Progenitor Proliferation Membrane Raft
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