IGFALS

Gene Name		insulin-like growth factor binding protein, acid labile subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Extracellular Vesicular Exosome
	Molecular Function	Insulin-like Growth Factor Binding
	Biological Process	Cell Adhesion Signal Transduction Cellular Protein Metabolic Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Diseases
GWAS		Insulin-like growth factors ( 21216879)
Protein-protein Interactions		4 interactors: IGF1 IGFBP3 IGFBP5 PDCD6
Entrez ID		3483
HPRD ID		03290
Ensembl ID		ENSG00000099769
Uniprot IDs		P35858 Q8TAY0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Smooth Muscle Cell Migration Regulation Of Smooth Muscle Cell Proliferation Regulation Of Glucose Metabolic Process Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Protein Kinase B Signaling Regulation Of Locomotion Regulation Of Cellular Component Movement Regulation Of Carbohydrate Metabolic Process Type B Pancreatic Cell Proliferation Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Ossification Regulation Of Cell Proliferation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase B Signaling Regulation Of Growth Regulation Of Protein Metabolic Process Negative Regulation Of Cell Proliferation Cell Proliferation Response To Heat Tissue Remodeling Positive Regulation Of Intracellular Signal Transduction Regulation Of Osteoblast Differentiation Regulation Of Signal Transduction Osteoblast Differentiation Positive Regulation Of Epithelial Cell Proliferation Apoptotic Process Gland Morphogenesis Regulation Of Signaling Programmed Cell Death Mammary Gland Development Cell Death Death Response To Temperature Stimulus Negative Regulation Of Cell Migration Regulation Of Ossification Prostate Gland Stromal Morphogenesis Glycolate Metabolic Process Skeletal Muscle Tissue Growth Negative Regulation Of Cell Motility Negative Regulation Of Cellular Component Movement Striated Muscle Cell Differentiation Positive Regulation Of Signal Transduction Negative Regulation Of Oocyte Development
Tagcloud ?		112g 11p15 1291delt 45m 6psi ccdc8 cul7 encompasses genetics ghi ghr height homozygous hypomethylation igf1 imprinting insensitive insensitivity ivs5ds justifying mupd7 obsl1 pseudoexon russell sds srs stat5b stature suspected