IGFALS

Description		insulin like growth factor binding protein acid labile subunit
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Insulin-like Growth Factor Ternary Complex Extracellular Exosome
	Molecular Function	Insulin-like Growth Factor Binding Signaling Receptor Activity
	Biological Process	Cell Adhesion Signal Transduction
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576) Insulin-like growth factors ( 21216879) Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		4 interacting genes: IGF1 IGFBP3 IGFBP5 PDCD6
Entrez ID		3483
HPRD ID		03290
Ensembl ID		ENSG00000099769
Uniprot IDs		P35858 Q8TAY0
PDB IDs		7WRQ
Enriched GO Terms of Interacting Partners?		Insulin-like Growth Factor Binding Protein Complex Insulin-like Growth Factor Ternary Complex Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Type B Pancreatic Cell Proliferation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Smooth Muscle Cell Migration Insulin-like Growth Factor II Binding Osteoblast Differentiation Insulin-like Growth Factor Binding Regulation Of Smooth Muscle Cell Proliferation Insulin-like Growth Factor I Binding Epithelial Cell Proliferation Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Fibronectin Binding Negative Regulation Of Smooth Muscle Cell Migration Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Growth Factor Binding Lung Alveolus Development Negative Regulation Of Signal Transduction Regulation Of Cell Growth Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Protein Metabolic Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Cell Population Proliferation Striated Muscle Cell Differentiation Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Tissue Remodeling Positive Regulation Of Cell Migration Response To Heat Positive Regulation Of Cell Motility Epithelial To Mesenchymal Transition Negative Regulation Of Protein Metabolic Process Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Growth Positive Regulation Of Locomotion Regulation Of Intracellular Signal Transduction Regulation Of Protein Modification Process Regulation Of Glucose Metabolic Process Enzyme-linked Receptor Protein Signaling Pathway Muscle Cell Differentiation Negative Regulation Of Oocyte Development Mesenchymal Cell Differentiation Negative Regulation Of Skeletal Muscle Hypertrophy
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