MACC1

Description		MET transcriptional regulator MACC1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Growth Factor Activity
	Biological Process	Signal Transduction Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Division
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide) ( 23648065) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Serum alkaline phosphatase levels ( 33547301) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		1 interacting genes: FASLG
Entrez ID		346389
HPRD ID		12381
Ensembl ID		ENSG00000183742
Uniprot IDs		Q6ZN28
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Phospholipid Translocation Cytoplasmic Vesicle Lumen Retinal Cell Programmed Cell Death Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Inflammatory Cell Apoptotic Process Necroptotic Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Positive Regulation Of Phospholipid Transport Intracellular Chloride Ion Homeostasis Endosomal Lumen Acidification Regulation Of Plasma Membrane Organization Death Receptor Binding Necroptotic Process Chloride Ion Homeostasis Programmed Necrotic Cell Death Programmed Cell Death Involved In Cell Development Monoatomic Anion Homeostasis Positive Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway T Cell Apoptotic Process Tumor Necrosis Factor Receptor Binding Positive Regulation Of ERBB Signaling Pathway Lymphocyte Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Membrane Lipid Distribution Leukocyte Apoptotic Process Regulation Of Endothelial Cell Apoptotic Process Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Intracellular PH Reduction Negative Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Neuron Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Caveola Cellular Response To Type II Interferon Positive Regulation Of Lipid Transport Regulation Of Intracellular PH Lysosomal Lumen Regulation Of Cellular PH Calcium Ion Transmembrane Import Into Cytosol Response To Type II Interferon Regulation Of PH Extrinsic Apoptotic Signaling Pathway Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Regulation Of Lipid Transport Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway
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