VWA2

Description		von Willebrand factor A domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Extracellular Matrix Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding
	Biological Process	Calcium-independent Cell-matrix Adhesion Regulation Of Insulin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Lymphocyte count ( 32888494) Monocyte count ( 32888494)
Interacting Genes		2 interacting genes: PTPN3 TRAF2
Entrez ID		340706
HPRD ID		16481
Ensembl ID		ENSG00000165816
Uniprot IDs		Q5GFL6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasmic Side Of Plasma Membrane TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Negative Regulation Of Catabolic Process Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex Negative Regulation Of Membrane Protein Ectodomain Proteolysis Regulation Of Membrane Depolarization During Action Potential CD27 Signaling Pathway Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Thioesterase Binding CD40 Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Interleukin-17-mediated Signaling Pathway CD40 Receptor Complex Positive Regulation Of JUN Kinase Activity TORC2 Signaling Cellular Response To Nitric Oxide Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Mitogen-activated Protein Kinase Kinase Kinase Binding Cellular Response To Reactive Nitrogen Species Intracellular Signaling Cassette Programmed Necrotic Cell Death Response To Nitric Oxide Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Sodium Ion Transmembrane Transport Sodium Channel Regulator Activity Positive Regulation Of T Cell Cytokine Production Positive Regulation Of MAP Kinase Activity Signal Transduction Involved In Regulation Of Gene Expression Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Tumor Necrosis Factor Receptor Binding Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Interleukin-2 Production Vesicle Membrane Regulation Of T Cell Cytokine Production Phosphotyrosine Residue Binding Regulation Of Membrane Depolarization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Sodium Ion Transport Cytoskeletal Protein Binding Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity
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