C2orf74

Description		chromosome 2 open reading frame 74
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463 22412388) High light scatter reticulocyte percentage of red cells ( 32888494) Inflammatory bowel disease ( 23128233)
Novel Interacting Genes		4 novel interacting genes: AHSA2P COMMD1 PNPT1 TMEM17
Interacting Genes		2 interacting genes: POT1 SMAGP
Entrez ID		339804
HPRD ID		19550
Ensembl ID		ENSG00000237651
Uniprot IDs		A8MZ97 C9JBF1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Nuclear Polyadenylation-dependent MRNA Catabolic Process Polyribonucleotide Nucleotidyltransferase Activity Positive Regulation Of Cholesterol Import Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding RRNA Transport RRNA Import Into Mitochondrion Positive Regulation Of Mitochondrial RNA Catabolic Process Mitochondrial Degradosome Mitochondrial MRNA Catabolic Process Negative Regulation Of Hypoxia-inducible Factor-1alpha Signaling Pathway Positive Regulation Of Endosome To Plasma Membrane Protein Transport Telomeric D-loop Binding Telomere Assembly Mitochondrial MRNA Polyadenylation Mitochondrial RNA 5'-end Processing Regulation Of Plasma Lipoprotein Particle Levels Single-stranded Telomeric DNA Binding RNA Import Into Mitochondrion Regulation Of Cholesterol Import Shelterin Complex Mitochondrial RNA 3'-end Processing Exoribonuclease Complex Positive Regulation Of MiRNA Catabolic Process Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Mitochondrial RNA Catabolic Process DEAD/H-box RNA Helicase Binding Poly(G) Binding Sodium Channel Inhibitor Activity Positive Regulation Of Endocytic Recycling Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Negative Regulation Of Sodium Ion Transmembrane Transport G-rich Strand Telomeric DNA Binding Plasma Membrane To Endosome Transport Telomeric Loop Disassembly Telomere Capping Negative Regulation Of Protein Localization To Cell Surface MKS Complex Negative Regulation Of Cellular Response To Hypoxia Protein Homotrimerization Negative Regulation Of Sodium Ion Transport Response To Growth Hormone Low-density Lipoprotein Particle Clearance Regulation Of DNA Strand Elongation
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