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ENPP7

Description ectonucleotide pyrophosphatase/phosphodiesterase 7
Image
GO Annotations Cellular Component
  • Golgi Apparatus
  • Plasma Membrane
  • Microvillus
  • Membrane
Molecular Function
  • Sphingomyelin Phosphodiesterase Activity
  • Protein Binding
  • Phosphoric Diester Hydrolase Activity
  • Zinc Ion Binding
  • Hydrolase Activity
  • Metal Ion Binding
Biological Process
  • Lipid Metabolic Process
  • Sphingomyelin Metabolic Process
  • Negative Regulation Of DNA Replication
  • Negative Regulation Of Cell Population Proliferation
  • Lipid Digestion
  • Positive Regulation Of Intestinal Cholesterol Absorption
  • Glycosphingolipid Catabolic Process
  • Fatty Acid Homeostasis
  • Regulation Of Intestinal Lipid Absorption
  • Positive Regulation Of Ceramide Biosynthetic Process
  • Positive Regulation Of Sphingomyelin Catabolic Process
Pathways
  • Glycosphingolipid catabolism
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Novel Interacting Genes 2 novel interacting genes: CIT SRC
Interacting Genes 5 interacting genes: BACH2 GOLGA2 KRTAP5-9 LRRC73 MTUS2
Entrez ID 339221
HPRD ID 10938
Ensembl ID ENSG00000182156
Uniprot IDs Q6UWV6
PDB IDs 5TCD 5UDY
Enriched GO Terms of Interacting Partners?
  • Negative Regulation Of Hippo Signaling
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