VSX2

Description		visual system homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Neuroblast Proliferation Negative Regulation Of Neuroblast Proliferation Visual Perception Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Central Nervous System Neuron Differentiation Camera-type Eye Development Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Retinal Bipolar Neuron Differentiation Retina Morphogenesis In Camera-type Eye
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Cervical high-risk human papilloma virus infection ( 33225922) Inflammatory bowel disease ( 28008999) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: PAX6 ZDHHC17
Entrez ID		338917
HPRD ID		08852
Ensembl ID		ENSG00000119614
Uniprot IDs		P58304
PDB IDs
Enriched GO Terms of Interacting Partners?		Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Axonogenesis Perforant Pathway To Dendrate Granule Cell Synapse Cell Projection Morphogenesis Neuron Projection Morphogenesis Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Habenula Development Pallium Development Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Oligodendrocyte Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Regionalization Lacrimal Gland Development Telencephalon Regionalization Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity Formation Of Anatomical Boundary Glial Cell Fate Specification Forebrain Neuron Fate Commitment Ventral Spinal Cord Development Iris Morphogenesis Type B Pancreatic Cell Differentiation Cornea Development In Camera-type Eye Salivary Gland Morphogenesis Regulation Of Neurotrophin TRK Receptor Signaling Pathway HMG Box Domain Binding Co-SMAD Binding Dorsal/ventral Axis Specification Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic Negative Regulation Of Neuroblast Proliferation Golgi-associated Vesicle Membrane Embryonic Camera-type Eye Morphogenesis Enteroendocrine Cell Differentiation Lipoprotein Transport Protein Palmitoylation Palmitoyltransferase Activity Regulation Of Modification Of Synaptic Structure Protein-cysteine S-palmitoyltransferase Activity RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of Neuroblast Proliferation Negative Regulation Of Neural Precursor Cell Proliferation Histone Acetyltransferase Binding Embryonic Eye Morphogenesis R-SMAD Binding Protein Lipidation Gland Morphogenesis
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