APBB2

Name	amyloid beta precursor protein binding family B member 2
Structure	No pdb structure
Interactors	9 interactors: APLP2 APP MAPK8 NFKB1 SMAD4 SMURF1 TP53 TRADD WWOX
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Endoplasmic Reticulum Golgi Apparatus Membrane Lamellipodium Growth Cone Synapse
	Molecular Function	Amyloid-beta Binding Protein Binding Molecular Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Regulation Of DNA-templated Transcription Smooth Muscle Contraction Axon Guidance Extracellular Matrix Organization Intracellular Signal Transduction Maintenance Of Lens Transparency Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Synapse Organization Negative Regulation Of Cell Cycle Phase Transition
GWAS	Dental caries ( 23259602 ) Glaucoma (primary open-angle) ( 31688885 ) Height ( 28552196 ) Iris color (L* coordinate) ( 29109912 ) Opioid sensitivity ( 24143882 ) Response to citalopram or escitalopram in depression ( 27622933 ) Severe insulin-resistant type 2 diabetes ( 34737425 )
Entrez ID	323
HPRD ID	04088
Ensembl ID	ENSG00000163697
Uniprot IDs	B4DJ88 B4E2F2 G5E9Y1 Q5I0G1 Q92870
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of MiRNA Metabolic Process Cell Surface Receptor Signaling Pathway Intracellular Signaling Cassette Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Transcription Coactivator Binding Histone Deacetylase Regulator Activity Signal Transduction Identical Protein Binding Intracellular Signal Transduction Positive Regulation Of MiRNA Metabolic Process Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of MiRNA Transcription Regulation Of Wnt Signaling Pathway Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Cardiac Muscle Cell Apoptotic Process I-SMAD Binding Enzyme Binding Transition Metal Ion Binding Platelet Alpha Granule Apoptotic Process Cellular Response To Oxygen-containing Compound Positive Regulation Of Signal Transduction Cytokine-mediated Signaling Pathway Central Nervous System Development Programmed Cell Death Positive Regulation Of Apoptotic Signaling Pathway Cell Death Regulation Of Hair Follicle Development Protein Serine/threonine Kinase Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Binding Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Inflammatory Response Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of RNA Metabolic Process Molecular Function Activator Activity R-SMAD Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Hair Cycle Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cellular Component Organization Non-canonical NF-kappaB Signal Transduction Response To Mechanical Stimulus Regulation Of Signal Transduction Positive Regulation Of Nucleobase-containing Compound Metabolic Process