HLA-DRB4

Description		major histocompatibility complex, class II, DR beta 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Endosome Membrane ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	MHC Class II Protein Complex Binding Peptide Antigen Binding
	Biological Process	Adaptive Immune Response Immune System Process Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Immune Response Antigen Processing And Presentation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Immune Response Positive Regulation Of T Cell Activation
Pathways		Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation Co-inhibition by PD-1 Interferon gamma signaling
Drugs		1D09C3 Coccidioides immitis spherule
Diseases
GWAS
Interacting Genes		3 interacting genes: ASMTL CTAG1B MAGEA6
Entrez ID		3126
HPRD ID		09986
Ensembl ID
Uniprot IDs		P13762 X5D2U9
PDB IDs
Enriched GO Terms of Interacting Partners?		DTTP Diphosphatase Activity UTP Diphosphatase Activity O-methyltransferase Activity Nucleoside Triphosphate Diphosphatase Activity TRNA Threonylcarbamoyladenosine Metabolic Process
Tagcloud ?