HLA-DOB

Gene Name		major histocompatibility complex, class II, DO beta
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Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Membrane Integral Component Of Membrane MHC Class II Protein Complex
	Molecular Function	MHC Class II Protein Complex Binding MHC Class II Receptor Activity
	Biological Process	Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response Signal Transduction Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Crohn's disease ( 23266558) Kawasaki disease ( 22446962)
Protein-protein Interactions		1 interactors: HLA-DMB
Entrez ID		3112
HPRD ID		08368
Ensembl ID		ENSG00000241106
Uniprot IDs		P13765 Q5QNS2
PDB IDs		4I0P
Enriched GO Terms of Interacting Partners?		Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly Positive Regulation Of T Cell Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Regulation Of T Cell Proliferation Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Cell-cell Adhesion Antigen Processing And Presentation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Cellular Protein Complex Assembly Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Cell Activation Regulation Of Cell Adhesion Cellular Macromolecular Complex Assembly Positive Regulation Of Immune Response Positive Regulation Of Cell Proliferation Regulation Of Immune Response Positive Regulation Of Immune System Process
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