HINT1

Gene Name		histidine triad nucleotide binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Cytoplasm Cytoskeleton Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Protein Kinase C Binding Hydrolase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Purine Ribonucleotide Catabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
Drugs		Adenosine monophosphate Guanosine-5\'-Monophosphate 5\'-O-(N-Ethyl-Sulfamoyl)Adenosine Adenosine-5\'-Ditungstate 8-Bromo-Adenosine-5\'-Monophosphate
Diseases
GWAS
Protein-protein Interactions		4 interactors: CDC16 MITF SP1 TRIM29
Entrez ID		3094
HPRD ID		03204
Ensembl ID
Uniprot IDs		P49773
PDB IDs		1AV5 1KPA 1KPB 1KPC 1KPE 1KPF 3TW2 4EQE 4EQG 4EQH
Enriched GO Terms of Interacting Partners?		Sequestering Of Nodal From Receptor Via Nodal Binding Transcription From RNA Polymerase II Promoter Negative Regulation Of Nodal Signaling Pathway Myeloid Cell Differentiation Determination Of Left/right Asymmetry In Lateral Mesoderm Regulation Of Nodal Signaling Pathway Sequestering Of Extracellular Ligand From Receptor Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Camera-type Eye Development Negative Regulation Of Activin Receptor Signaling Pathway Positive Regulation By Host Of Viral Transcription Eye Development Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Process Involved In Female Pregnancy Lateral Mesoderm Development Enucleate Erythrocyte Differentiation Negative Regulation Of Cellular Metabolic Process Extracellular Negative Regulation Of Signal Transduction Transcription, DNA-templated Sensory Organ Development Atrial Septum Development Megakaryocyte Differentiation Regulation Of Activin Receptor Signaling Pathway Protein K11-linked Ubiquitination RNA Biosynthetic Process Definitive Hemopoiesis Hemopoiesis Trophectodermal Cell Differentiation Positive Regulation Of Cellular Metabolic Process Immune System Development Interaction With Symbiont Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Negative Regulation Of Transcription From RNA Polymerase II Promoter Melanocyte Differentiation Mitotic Spindle Checkpoint Blastocyst Formation Embryonic Camera-type Eye Morphogenesis Negative Regulation Of Chromosome Segregation Negative Regulation Of BMP Signaling Pathway Embryonic Eye Morphogenesis Osteoclast Differentiation Positive Regulation Of Viral Transcription Neuroepithelial Cell Differentiation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition RNA Metabolic Process Ventricular Septum Development
Tagcloud ?		attenuating beta1 capable catenin ccl4 dawley engineering exists fibrosis histidine histopathological hydroxyproline liver lowered pathogenic simultaneously sma smad smad3 smad7 sought sprague subcutaneous tetrachloride tgf transforming triad vital