NCKAP1L

Name	NCK associated protein 1 like
Structure	No pdb structure
Interactors	2 interactors: GAS7 PRPF40A
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Secretory Granule Membrane SCAR Complex Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Protein Kinase Activator Activity Protein-containing Complex Binding TORC2 Complex Binding
	Biological Process	Cell Morphogenesis B Cell Homeostasis Myeloid Cell Homeostasis Positive Regulation Of Leukocyte Migration Chemotaxis Response To Xenobiotic Stimulus Cell Migration Maintenance Of Cell Polarity Cell Projection Assembly Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Positive Regulation Of B Cell Proliferation Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Positive Regulation Of Cell Adhesion Mediated By Integrin Erythrocyte Homeostasis Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation T Cell Homeostasis Negative Regulation Of Apoptotic Process Negative Regulation Of Cytotoxic T Cell Degranulation Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of B Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Erythrocyte Differentiation Neuron Projection Morphogenesis Erythrocyte Development B Cell Receptor Signaling Pathway Positive Regulation Of Phagocytosis, Engulfment Protein-containing Complex Assembly Actin Polymerization-dependent Cell Motility Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Neutrophil Migration Positive Regulation Of TORC2 Signaling
Pathways	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
GWAS	Hip circumference adjusted for BMI ( 28552196 ) Obesity-related traits ( 23251661 )
Entrez ID	3071
HPRD ID	00781
Ensembl ID	ENSG00000123338
Uniprot IDs	P55160
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Clathrin Coat Assembly U2-type Prespliceosome U1 SnRNP MRNA Cis Splicing, Via Spliceosome