NCKAP1L

Gene Name		NCK-associated protein 1-like
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Integral Component Of Plasma Membrane Membrane SCAR Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Kinase Activator Activity Rac GTPase Activator Activity Protein Complex Binding
	Biological Process	B Cell Homeostasis Myeloid Cell Homeostasis Protein Complex Assembly Chemotaxis Maintenance Of Cell Polarity Neutrophil Chemotaxis Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Positive Regulation Of B Cell Proliferation Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Positive Regulation Of Rac GTPase Activity Positive Regulation Of Cell Adhesion Mediated By Integrin Negative Regulation Of Myosin-light-chain-phosphatase Activity Positive Regulation Of T Cell Proliferation Positive Regulation Of Phosphorylation Response To Drug T Cell Homeostasis Negative Regulation Of Apoptotic Process Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of B Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Protein Kinase Activity Erythrocyte Development B Cell Receptor Signaling Pathway Positive Regulation Of Phagocytosis, Engulfment Actin Polymerization-dependent Cell Motility Positive Regulation Of Neutrophil Chemotaxis
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		2 interactors: GAS7 PRPF40A
Entrez ID		3071
HPRD ID		00781
Ensembl ID		ENSG00000123338
Uniprot IDs		P55160
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Shape Regulation Of Cell Morphogenesis Regulation Of Cell Cycle Cytoskeleton Organization Cell Cycle Actin Filament Polymerization Regulation Of Cytokinesis Actin Filament Bundle Assembly
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