HDGF

Gene Name		hepatoma-derived growth factor
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Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytoplasm Transcriptional Repressor Complex
	Molecular Function	Nucleotide Binding RNA Polymerase II Transcription Corepressor Activity Transcription Corepressor Binding DNA Binding Growth Factor Activity Heparin Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Signal Transduction Cell Proliferation Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: JUN SMAD4 XBP1
Entrez ID		3068
HPRD ID		02079
Ensembl ID		ENSG00000143321
Uniprot IDs		P51858
PDB IDs		1RI0 2NLU
Enriched GO Terms of Interacting Partners?		Gland Development Epithelial Cell Differentiation Cellular Response To Growth Factor Stimulus SMAD Protein Signal Transduction Response To Growth Factor Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Cell Differentiation Cardiovascular System Development Transcription From RNA Polymerase II Promoter Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Neuron Development Negative Regulation Of Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Regulation Of Protein Phosphorylation Epithelium Development Response To Abiotic Stimulus Cellular Response To Starvation Negative Regulation Of Transcription, DNA-templated Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Neuron Differentiation Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Lactation Positive Regulation Of Plasma Cell Differentiation Epithelial Cell Maturation Involved In Salivary Gland Development Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Cellular Response To Potassium Ion Starvation Serotonin Secretion, Neurotransmission Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Epithelial Cell Proliferation Liver Development Positive Regulation Of Intracellular Protein Transport Response To Endoplasmic Reticulum Stress Regulation Of Protein Import Into Nucleus Regulation Of Organ Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Nutrient Levels Regulation Of Phosphorylation Response To Starvation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Response To Transforming Growth Factor Beta Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport
Tagcloud ?		annealing apparently bm classifier clinicopathological cohort cohorts complementary deoxyribonucleic discovery distant extension hr immediate interventional ligation likelihood location neu optimize predictive qrt rad51 refined symptomatic tpr trastuzumab validation visceral