SERPIND1

Description		serpin family D member 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Extracellular Exosome
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Peptidase Inhibitor Activity
	Biological Process	Chemotaxis Blood Coagulation Hemostasis
Pathways		Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Ardeparin Zinc Sulodexide Copper Bemiparin Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Inherited thrombophilia
GWAS
Interacting Genes		5 interacting genes: APP CFTR CTSG ELANE F2
Entrez ID		3053
HPRD ID		00795
Ensembl ID		ENSG00000099937
Uniprot IDs		P05546 Q8IVC0
PDB IDs		1JMJ 1JMO 2NAT 2NCU 2NCV 2NCW 6J12 6KBO 6KBV
Enriched GO Terms of Interacting Partners?		Neutrophil-mediated Killing Of Bacterium Neutrophil Mediated Immunity Heparin Binding Killing By Host Of Symbiont Cells Biological Process Involved In Interaction With Symbiont Defense Response To Fungus Response To Fungus Neutrophil-mediated Killing Of Gram-negative Bacterium Leukocyte Mediated Cytotoxicity Immune Effector Process Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Receptor Ligand Activity Serine-type Peptidase Activity Killing Of Cells Of Another Organism Intracellular Chemical Homeostasis Leukocyte Mediated Immunity Serine-type Endopeptidase Activity Response To Yeast Antimicrobial Humoral Response Cellular Homeostasis Cell Killing Defense Response To Symbiont Defense Response To Other Organism Chemical Homeostasis Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Protein Transport Humoral Immune Response Regulation Of Monoatomic Ion Transmembrane Transport Defense Response To Bacterium Ligand-gated Ion Channel Signaling Pathway Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Extracellular Matrix Disassembly Response To Other Organism Regulation Of Platelet Activation Negative Regulation Of Multicellular Organismal Process Cellular Response To CAMP Immune Response Regulation Of Monoatomic Ion Transport Inorganic Ion Homeostasis Antibacterial Humoral Response Response To Bacterium Acute Inflammatory Response Homeostatic Process Regulation Of Multicellular Organismal Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
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