SERPIND1

Gene Name		serpin peptidase inhibitor, clade D (heparin cofactor), member 1
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Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Heparin Binding
	Biological Process	Chemotaxis Blood Coagulation Negative Regulation Of Endopeptidase Activity
Pathways		Common Pathway Intrinsic Pathway Formation of Fibrin Clot (Clotting Cascade)
Drugs		Ardeparin Alpha-D-Mannose Sulodexide
Diseases
GWAS
Protein-protein Interactions		4 interactors: APP CTSG ELANE F2
Entrez ID		3053
HPRD ID		00795
Ensembl ID		ENSG00000099937
Uniprot IDs		P05546 Q8IVC0
PDB IDs		1JMJ 1JMO
Enriched GO Terms of Interacting Partners?		Killing By Host Of Symbiont Cells Regulation Of Growth Neutrophil Mediated Immunity Killing Of Cells Of Other Organism Negative Regulation Of Growth Of Symbiont In Host Defense Response To Fungus Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Defense Response Interaction With Symbiont Leukocyte Mediated Cytotoxicity Extracellular Matrix Organization Extracellular Structure Organization Response To Fungus Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Ion Homeostasis Acute Inflammatory Response Immune System Process Regulation Of Protein Metabolic Process Extracellular Matrix Disassembly Cellular Homeostasis Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Chemical Homeostasis Negative Regulation Of Protein Metabolic Process Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Synaptic Growth At Neuromuscular Junction Regulation Of Protein Phosphorylation Defense Response To Bacterium Platelet Activation Positive Regulation Of Cellular Protein Metabolic Process Response To Stress Collateral Sprouting In Absence Of Injury Leukocyte Migration Positive Regulation Of Protein Metabolic Process Locomotion Negative Regulation Of Growth Immune Response Regulation Of Phosphorylation Leukocyte Mediated Immunity Homeostatic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Chemokine Biosynthetic Process Negative Regulation Of Interleukin-8 Biosynthetic Process Negative Regulation Of Neurogenesis
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