RAX

Description		retina and anterior neural fold homeobox
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Brain Development Visual Perception Hypothalamus Development Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II Limb Development
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Chronotype ( 27494321) Macular thickness ( 30535121) Morning vs. evening chronotype ( 27494321) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Novel Interacting Genes		1 novel interacting genes: ALPK2
Interacting Genes		1 interacting genes: PAX6
Entrez ID		30062
HPRD ID		03530
Ensembl ID		ENSG00000134438
Uniprot IDs		Q9Y2V3
PDB IDs
Enriched GO Terms of Interacting Partners?		Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Negative Regulation Of Wnt Signaling Pathway Involved In Heart Development Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Forebrain Neuron Fate Commitment Habenula Development Oligodendrocyte Cell Fate Specification Ventral Spinal Cord Development Animal Organ Morphogenesis Pallium Development Formation Of Anatomical Boundary Iris Morphogenesis Glial Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Regionalization Lacrimal Gland Development Telencephalon Regionalization Epicardium Morphogenesis Type B Pancreatic Cell Differentiation Cornea Development In Camera-type Eye Salivary Gland Morphogenesis HMG Box Domain Binding Co-SMAD Binding Regulation Of Timing Of Cell Differentiation Negative Regulation Of Neuroblast Proliferation Dorsal/ventral Axis Specification Regulation Of Development, Heterochronic Embryonic Camera-type Eye Morphogenesis Enteroendocrine Cell Differentiation RNA Polymerase II Core Promoter Sequence-specific DNA Binding Cell Development Negative Regulation Of Developmental Process Negative Regulation Of Neural Precursor Cell Proliferation Histone Acetyltransferase Binding Embryonic Eye Morphogenesis R-SMAD Binding Positive Regulation Of Neuroblast Proliferation Gland Morphogenesis Pituitary Gland Development Astrocyte Differentiation Photoreceptor Cell Development Establishment Of Spindle Orientation Regulation Of Neuroblast Proliferation Lens Development In Camera-type Eye Signal Transduction Involved In Regulation Of Gene Expression Eye Photoreceptor Cell Development Transcription Coregulator Binding Neuron Fate Commitment Establishment Of Mitotic Spindle Localization
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