PARVB

Gene Name		parvin, beta
Image
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Z Disc Lamellipodium
	Molecular Function	Actin Binding Protein Binding
	Biological Process	Cell Adhesion Cell Projection Assembly Lamellipodium Assembly Actin Cytoskeleton Reorganization Cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape
Pathways		Cell junction organization Regulation of cytoskeletal remodeling and cell spreading by IPP complex components Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Hematological and biochemical traits ( 20139978) Non-alcoholic fatty liver disease ( 23535911) Nonalcoholic fatty liver disease ( 22719876)
Protein-protein Interactions		2 interactors: ARHGEF6 ILK
Entrez ID		29780
HPRD ID		16284
Ensembl ID		ENSG00000188677
Uniprot IDs		Q9HBI1
PDB IDs		4EDL 4EDM 4EDN
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Fibroblast Migration Extracellular Fibril Organization Negative Regulation Of Striated Muscle Cell Apoptotic Process Negative Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Myoblast Differentiation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Cell Projection Organization Myelin Assembly Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of BMP Signaling Pathway Positive Regulation Of Dendrite Morphogenesis Platelet Aggregation Protein Kinase B Signaling Positive Regulation Of Axon Extension Regulation Of Myoblast Differentiation Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Smooth Muscle Cell Proliferation Substrate Adhesion-dependent Cell Spreading Regulation Of Apoptotic Process Myelination In Peripheral Nervous System Lamellipodium Assembly Schwann Cell Development Positive Regulation Of Catalytic Activity Lamellipodium Organization Negative Regulation Of Neural Precursor Cell Proliferation Regulation Of Cell Death Positive Regulation Of Cell-matrix Adhesion Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Dendrite Development Branching Involved In Ureteric Bud Morphogenesis Schwann Cell Differentiation Regulation Of Intracellular Signal Transduction Ureteric Bud Morphogenesis Regulation Of Axon Extension Regulation Of Dendrite Morphogenesis Cell Aging Positive Regulation Of Osteoblast Differentiation Phosphorylation Intracellular Signal Transduction Positive Regulation Of Axonogenesis Positive Regulation Of Protein Kinase B Signaling Cellular Component Assembly Nephron Morphogenesis Regulation Of BMP Signaling Pathway Renal Tubule Morphogenesis JNK Cascade Positive Regulation Of Muscle Cell Differentiation
Tagcloud ?		alt anthropometric apoc3 cms col13a1 consent corrections efcab4b infiltration iu nafld ncan obtaining patatin pnpla3 pzp rs2073080 rs2143571 rs2228603 rs2854117 rs343062 rs6487679 rs6591182 rs738409 samm50 sequenom snps transaminase triglyceride