GSTA2

Gene Name		glutathione S-transferase alpha 2
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Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Glutathione Transferase Activity
	Biological Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Epithelial Cell Differentiation Small Molecule Metabolic Process Glutathione Derivative Biosynthetic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs		Glutathione Chloroquine
Diseases
GWAS
Protein-protein Interactions		2 interactors: GSTA1 GSTA4
Entrez ID		2939
HPRD ID		00709
Ensembl ID		ENSG00000244067
Uniprot IDs		A8K987 P09210
PDB IDs		1AGS 2VCT 2WJU 4ACS
Enriched GO Terms of Interacting Partners?		Glutathione Derivative Biosynthetic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Peptide Metabolic Process Cellular Modified Amino Acid Metabolic Process Cellular Amide Metabolic Process Sulfur Compound Metabolic Process Small Molecule Metabolic Process
Tagcloud ?		antigen appear approximate bp constitutive contain detoxification downregulates element fragment glutathione gsta1 gstalpha ikaros includes missing named prb promoters repress repression require resemble sufficient sv40 tagr transferase transient weights