RANGRF

Description		RAN guanine nucleotide release factor
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Rough Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Intercalated Disc Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Sodium Channel Regulator Activity Small GTPase Binding Transmembrane Transporter Binding Channel Activator Activity
	Biological Process	Regulation Of Heart Rate Regulation Of Membrane Depolarization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Protein Exit From Endoplasmic Reticulum Heart Contraction Mitotic Spindle Assembly Regulation Of Bundle Of His Cell Action Potential Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: PTPN11 RAN RANBP1 ZDHHC17
Entrez ID		29098
HPRD ID		06407
Ensembl ID		ENSG00000108961
Uniprot IDs		Q9HD47
PDB IDs		5YFG
Enriched GO Terms of Interacting Partners?		Cadherin Binding Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Regulation Of Intracellular Protein Transport Regulation Of Nucleocytoplasmic Transport Intestinal Epithelial Cell Migration Axonogenesis RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Nuclear Pore Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Cerebellar Cortex Formation Positive Regulation Of Mitotic Centrosome Separation Cell Projection Morphogenesis Negative Regulation Of Neutrophil Activation Regulation Of ERK1 And ERK2 Cascade Neuron Projection Morphogenesis Negative Regulation Of Glucocorticoid Secretion Regulation Of Intracellular Transport Nuclear Transport Nucleocytoplasmic Transport Ribosomal Small Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Nuclear Envelope RNA Import Into Nucleus Regulation Of Mitotic Centrosome Separation Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity Microvillus Organization Non-membrane Spanning Protein Tyrosine Phosphatase Activity Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Atrioventricular Canal Development Regulation Of Neutrophil Activation Peptide Hormone Receptor Binding Negative Regulation Of Cell Adhesion Mediated By Integrin Bergmann Glial Cell Differentiation Positive Regulation Of Cell Cycle Neutrophil Activation Involved In Immune Response Cellular Response To Mineralocorticoid Stimulus Nuclear Export Signal Receptor Activity Protein Localization To Nucleolus Pre-miRNA Binding Importin-alpha Family Protein Binding Ribosomal Subunit Export From Nucleus Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Growth Hormone Secretion Golgi-associated Vesicle Membrane
Tagcloud ?