GRIK4

Description		glutamate ionotropic receptor kainate type subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Kainate Selective Glutamate Receptor Complex Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Hippocampal Mossy Fiber To CA3 Synapse Postsynaptic Density Membrane
	Molecular Function	Monoatomic Ion Channel Activity Ligand-gated Monoatomic Ion Channel Activity Kainate Selective Glutamate Receptor Activity Signaling Receptor Activity Ligand-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Monoatomic Ion Transport Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Monoatomic Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Modulation Of Chemical Synaptic Transmission Regulation Of Postsynaptic Membrane Potential Regulation Of Presynaptic Membrane Potential
Pathways		Activation of Ca-permeable Kainate Receptor
Drugs		Glutamic acid Butabarbital Topiramate
Diseases
GWAS		Attention deficit hyperactivity disorder ( 23728934) Cognitive performance ( 20125193) Lateral ventricle volume ( 31530798) Post bronchodilator FEV1 in COPD ( 26634245)
Interacting Genes		4 interacting genes: GRIK1 GRIK2 GRIK3 RAB5A
Entrez ID		2900
HPRD ID		02613
Ensembl ID		ENSG00000149403
Uniprot IDs		A0A8D9PH79 A0A8D9UJ88 A6H8K8 B2RAP6 Q16099
PDB IDs
Enriched GO Terms of Interacting Partners?		Kainate Selective Glutamate Receptor Complex Kainate Selective Glutamate Receptor Activity Glutamate-gated Calcium Ion Channel Activity Glutamate-gated Receptor Activity Ionotropic Glutamate Receptor Signaling Pathway Ligand-gated Monoatomic Ion Channel Activity Ligand-gated Ion Channel Signaling Pathway Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Terminal Bouton Synaptic Transmission, Glutamatergic Glutamate Receptor Signaling Pathway Regulation Of Synaptic Transmission, Glutamatergic Modulation Of Chemical Synaptic Transmission Regulation Of Postsynaptic Membrane Potential Postsynaptic Density Membrane Negative Regulation Of Synaptic Transmission, Glutamatergic Presynaptic Membrane Glutamate Receptor Activity Monoatomic Ion Channel Activity Calcium-mediated Signaling Ligand-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Postsynaptic Membrane Dendrite Cytoplasm Regulation Of Long-term Neuronal Synaptic Plasticity Signaling Receptor Activity Regulation Of Presynaptic Membrane Potential Chemical Synaptic Transmission Trans-synaptic Signaling Negative Regulation Of Synaptic Transmission Synaptic Signaling Axon Regulation Of Membrane Potential Regulation Of Neuronal Synaptic Plasticity Dendrite Cell-cell Signaling Cell Surface Receptor Signaling Pathway Signaling Cell Communication Mossy Fiber Rosette Detection Of Cold Stimulus Involved In Thermoception Extracellularly Glutamate-gated Ion Channel Activity Monoatomic Ion Transmembrane Transport Perikaryon Intracellular Signaling Cassette Regulation Of Biological Quality Monoatomic Ion Transport Synapse Protein Localization To Early Endosome Regulation Of Synaptic Plasticity Ionotropic Glutamate Receptor Complex
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