GRIK4

Gene Name		glutamate receptor, ionotropic, kainate 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite Kainate Selective Glutamate Receptor Complex Presynaptic Membrane Terminal Bouton Perikaryon Postsynaptic Membrane
	Molecular Function	Extracellular-glutamate-gated Ion Channel Activity Kainate Selective Glutamate Receptor Activity
	Biological Process	Transport Glutamate Receptor Signaling Pathway Synaptic Transmission Response To Corticosteroid Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic
Pathways		Activation of Kainate Receptors upon glutamate binding Activation of Ca-permeable Kainate Receptor Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ionotropic activity of Kainate Receptors Transmission across Chemical Synapses
Drugs		L-Glutamic Acid
Diseases
GWAS		Attention deficit hyperactivity disorder ( 23728934) Cognitive performance ( 20125193)
Protein-protein Interactions		2 interactors: GRIK2 RAB5A
Entrez ID		2900
HPRD ID		02613
Ensembl ID		ENSG00000149403
Uniprot IDs		Q16099
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Synaptic Vesicle Exocytosis Regulation Of Synaptic Vesicle Transport Regulation Of Neuronal Synaptic Plasticity Regulation Of Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Synaptic Plasticity Regulation Of Synaptic Transmission Regulation Of Endosome Size Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Vesicle-mediated Transport Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Synaptic Transmission Regulation Of Secretion Protein Retention In ER Lumen Regulation Of Short-term Neuronal Synaptic Plasticity Maintenance Of Protein Localization In Endoplasmic Reticulum Regulation Of Inhibitory Postsynaptic Membrane Potential Negative Regulation Of Synaptic Transmission, Glutamatergic Cell-cell Signaling Intracellular Protein Transport Early Endosome To Late Endosome Transport Regulation Of Cellular Localization Positive Regulation Of Smooth Muscle Cell Migration Neuronal Action Potential Membrane Hyperpolarization Behavioral Fear Response Regulation Of Vesicle Fusion Synaptic Vesicle Recycling Fear Response Cellular Protein Localization Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Smooth Muscle Cell Migration Protein Transport Receptor Internalization Establishment Of Protein Localization Regulation Of Filopodium Assembly Receptor Clustering Intracellular Transport Transmission Of Nerve Impulse Neuron Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Rab Protein Signal Transduction Positive Regulation Of Neuron Apoptotic Process Glutamate Receptor Signaling Pathway Cellular Response To Glucose Stimulus Positive Regulation Of Exocytosis Negative Regulation Of Synaptic Transmission Regulation Of Synaptic Transmission, Glutamatergic
Tagcloud ?		500x abl actionable alk amplifications asxl1 copy correctly coverage deep deletions duplications eml4 formalin gains guide insertions losses mixing mll oncoplex paraffin pik3r1 rearrangements ros1 sgcz underdeveloped uw validate