ASTE1

Description		asteroid structure-specific endonuclease 1
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Single-stranded DNA Endodeoxyribonuclease Activity Nuclease Activity DNA Endonuclease Activity Protein Binding Hydrolase Activity 3' Overhang Single-stranded DNA Endodeoxyribonuclease Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Double-strand Break Repair Via Nonhomologous End Joining DNA Recombination
Pathways
Drugs
Diseases
GWAS		Phenylephrine infusion rate during anesthesia ( 31455332) Restless legs syndrome ( 29029846)
Novel Interacting Genes		1 novel interacting genes: NPHP3
Interacting Genes		1 interacting genes: XRCC4
Entrez ID		28990
HPRD ID		11038
Ensembl ID		ENSG00000034533
Uniprot IDs		D6RG30 Q2TB18
PDB IDs
Enriched GO Terms of Interacting Partners?		FHA Domain Binding Determination Of Stomach Left/right Asymmetry Determination Of Intestine Left/right Asymmetry Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of Phospholipid Translocation DNA-dependent Protein Kinase-DNA Ligase 4 Complex Positive Regulation Of Ligase Activity DNA Ligase IV Complex Maintenance Of Animal Organ Identity Ureter Development Ciliary Inversin Compartment Determination Of Digestive Tract Left/right Asymmetry Determination Of Pancreatic Left/right Asymmetry Convergent Extension Involved In Gastrulation Determination Of Liver Left/right Asymmetry Immunoglobulin V(D)J Recombination Nonhomologous End Joining Complex Atrial Septum Development Positive Regulation Of Phospholipid Transport Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Convergent Extension Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Kidney Morphogenesis Cellular Response To Lithium Ion Regulation Of Plasma Membrane Organization Response To Lithium Ion V(D)J Recombination Regulation Of Non-canonical Wnt Signaling Pathway Protein Localization To Site Of Double-strand Break Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Base-excision Repair Photoreceptor Cell Maintenance Regulation Of Membrane Lipid Distribution Somatic Cell DNA Recombination Somatic Diversification Of Immunoglobulins Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cardiac Septum Development Extracellular Transport Ciliary Base Non-motile Cilium Assembly Double-strand Break Repair Via Nonhomologous End Joining Heart Looping Embryonic Heart Tube Morphogenesis Positive Regulation Of Lipid Transport Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Site Of Double-strand Break Lung Development
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