GPX2

Gene Name		glutathione peroxidase 2 (gastrointestinal)
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Glutathione Peroxidase Activity Electron Carrier Activity
	Biological Process	Response To Reactive Oxygen Species Temperature Homeostasis Negative Regulation Of Inflammatory Response To Antigenic Stimulus Response To Symbiotic Bacterium Interaction With Symbiont Oxidation-reduction Process
Pathways		Arachidonic acid metabolism Synthesis of 5-eicosatetraenoic acids Metabolism of lipids and lipoproteins Synthesis of 12-eicosatetraenoic acid derivatives Synthesis of 15-eicosatetraenoic acid derivatives Detoxification of Reactive Oxygen Species
Drugs		Glutathione
Diseases
GWAS
Protein-protein Interactions		3 interactors: MYC PSMB2 TP53
Entrez ID		2877
HPRD ID		11818
Ensembl ID		ENSG00000176153
Uniprot IDs		P18283
PDB IDs		2HE3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Cell Cycle Response To Gamma Radiation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cellular Response To Drug Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To UV Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Signal Transduction In Response To DNA Damage Cellular Response To Light Stimulus Mitotic DNA Damage Checkpoint Cellular Response To DNA Damage Stimulus Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Arrest Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Stem Cell Proliferation Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Cell Cycle Process Cell Death Death Regulation Of G1/S Transition Of Mitotic Cell Cycle Response To UV Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Signal Transduction Cellular Response To Radiation Notch Signaling Pathway Response To Ionizing Radiation Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Cell Cycle Arrest DNA Damage Checkpoint Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Negative Regulation Of Signaling Mitotic Cell Cycle Checkpoint Positive Regulation Of Protein Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus
Tagcloud ?		adapt adaptive ampk antioxidants avoids biogenesis comprehensively consumed crisis depolarization devoid etc fueling futile gpx1 gpx5 gr hampered handling paralleled peroxidation pgc1 prominently pumps slower sod1 sod2 strictly ultra