GPX2

Name	glutathione peroxidase 2
Structure
Novel Interactors	1 novel interactors: SYNE1
Interactors	3 interactors: MYC PSMB2 TP53
GO Annotations	Cellular Component	Cytoplasm Cytosol Intercellular Bridge Mitotic Spindle
	Molecular Function	Peroxidase Activity Glutathione Peroxidase Activity Electron Transfer Activity Oxidoreductase Activity Phospholipid-hydroperoxide Glutathione Peroxidase Activity
	Biological Process	Response To Oxidative Stress Cellular Oxidant Detoxification
Pathways	Synthesis of 5-eicosatetraenoic acids Synthesis of 12-eicosatetraenoic acid derivatives Synthesis of 15-eicosatetraenoic acid derivatives Detoxification of Reactive Oxygen Species TP53 Regulates Metabolic Genes
Drugs	Glutathione Glutathione Glutathione disulfide Benzoyl peroxide
GWAS	No GWAS studies recorded
Entrez ID	2877
HPRD ID	11818
Ensembl ID	ENSG00000176153
Uniprot IDs	P18283
PDB IDs	2HE3
GO Terms Enriched among Interactors ?	Core Promoter Sequence-specific DNA Binding Positive Regulation Of Lymphocyte Apoptotic Process Lymphocyte Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Leukocyte Apoptotic Process Negative Regulation Of Fibroblast Proliferation Regulation Of Lymphocyte Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Xenobiotic Stimulus Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Leukocyte Apoptotic Process T Cell Proliferation Positive Regulation Of DNA-templated Transcription Initiation Regulation Of MiRNA Transcription Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Cis-regulatory Region Sequence-specific DNA Binding Cellular Response To Light Stimulus Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Cellular Response To UV Regulation Of MiRNA Metabolic Process Muscle Cell Differentiation Regulation Of Fibroblast Proliferation Regulation Of Telomere Maintenance Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Lymphocyte Proliferation Mononuclear Cell Proliferation Regulation Of Signal Transduction By P53 Class Mediator Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Myc-Max Complex Positive Regulation Of Apoptotic Signaling Pathway Leukocyte Proliferation Regulation Of Acinar Cell Proliferation Oligodendrocyte Apoptotic Process Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Response To UV Cellular Response To Oxygen Levels NK T Cell Proliferation Cellular Response To Radiation Intrinsic Apoptotic Signaling Pathway Nucleolus