SLC26A11

Description		solute carrier family 26 member 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosome Lysosomal Membrane Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Chloride Channel Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Monoatomic Anion Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Antiporter Activity Chloride:bicarbonate Antiporter Activity
	Biological Process	Monoatomic Ion Transport Oxalate Transport Transmembrane Transport Inorganic Anion Transmembrane Transport Sulfate Transmembrane Transport Chloride Transmembrane Transport
Pathways		Transport and metabolism of PAPS Inorganic anion exchange by SLC26 transporters
Drugs
Diseases
GWAS		Interleukin-1-receptor antagonist levels ( 22205395) Ischemic stroke ( 26732560)
Interacting Genes		3 interacting genes: C5AR2 CFTR SMIM1
Entrez ID		284129
HPRD ID		11569
Ensembl ID		ENSG00000181045
Uniprot IDs		Q86WA9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Complement Component C5a Receptor Activity Positive Regulation Of Enamel Mineralization Complement Component C5a Signaling Pathway Transepithelial Water Transport Negative Regulation Of Neutrophil Chemotaxis Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Negative Regulation Of Neutrophil Migration Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Complement Receptor Activity Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Complement Receptor Mediated Signaling Pathway Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Negative Regulation Of Leukocyte Chemotaxis Cell Surface Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Regulation Of Neutrophil Chemotaxis Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Regulation Of Neutrophil Migration Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Negative Regulation Of Chemotaxis Negative Regulation Of Interleukin-6 Production
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