PCSK1N

Description		proprotein convertase subtilisin/kexin type 1 inhibitor
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Trans-Golgi Network Secretory Granule
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Signaling Receptor Binding
	Biological Process	Response To Dietary Excess Neuropeptide Signaling Pathway Response To Cold Peptide Hormone Processing
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 30718926)
Interacting Genes		2 interacting genes: PCSK1 RAD51
Entrez ID		27344
HPRD ID		02320
Ensembl ID		ENSG00000102109
Uniprot IDs		Q9UHG2
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Recombination-dependent Replication Fork Processing Response To Glucoside DNA Strand Exchange Activity Presynaptic Intermediate Filament Cytoskeleton DNA Strand Invasion Nuclear Ubiquitin Ligase Complex DNA Recombinase Assembly Cellular Response To Cisplatin Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Response To Cisplatin Cellular Response To Camptothecin Response To Glycoside Insulin Processing Double-strand Break Repair Involved In Meiotic Recombination Cellular Response To Hydroxyurea Response To Hydroxyurea Lateral Element Telomere Maintenance Via Recombination Insulin Metabolic Process ATP-dependent DNA Damage Sensor Activity Single-stranded DNA Helicase Activity Mitotic Recombination Peptide Biosynthetic Process Regulation Of DNA Damage Checkpoint DNA Polymerase Binding Reciprocal Meiotic Recombination Response To X-ray Cellular Response To Gamma Radiation Telomere Maintenance Via Telomere Lengthening Nuclear Chromosome ATP-dependent Activity, Acting On DNA Condensed Chromosome Peptide Hormone Processing Replication Fork Processing Cellular Response To Alkaloid Meiosis I Homologous Recombination Interstrand Cross-link Repair Signaling Receptor Ligand Precursor Processing Condensed Nuclear Chromosome Male Germ Cell Nucleus Response To Gamma Radiation Chromosome Organization Involved In Meiotic Cell Cycle Peptide Metabolic Process Meiosis I Cell Cycle Process Cellular Response To Ionizing Radiation Meiotic Nuclear Division Regulation Of Double-strand Break Repair Via Homologous Recombination Identical Protein Binding Endopeptidase Activity
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