MOCS3

Description		molybdenum cofactor synthesis 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Catalytic Activity Thiosulfate-cyanide Sulfurtransferase Activity Protein Binding ATP Binding Ubiquitin-like Modifier Activating Enzyme Activity Transferase Activity Nucleotidyltransferase Activity Sulfurtransferase Activity URM1 Activating Enzyme Activity Metal Ion Binding Molybdopterin-synthase Sulfurtransferase Activity Molybdopterin-synthase Adenylyltransferase Activity Adenylyltransferase Activity
	Biological Process	TRNA Wobble Uridine Modification TRNA Wobble Position Uridine Thiolation Mo-molybdopterin Cofactor Biosynthetic Process TRNA Processing Protein Urmylation TRNA Thio-modification
Pathways		Molybdenum cofactor biosynthesis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756)
Novel Interacting Genes		1 novel interacting genes: SLC9A8
Interacting Genes		3 interacting genes: EXOSC6 MOCS2 XRN2
Entrez ID		27304
HPRD ID		10092
Ensembl ID		ENSG00000124217
Uniprot IDs		O95396
PDB IDs		3I2V
Enriched GO Terms of Interacting Partners?		Molybdopterin Cofactor Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process Molybdopterin Synthase Activity Molybdopterin Synthase Complex Molybdopterin Cofactor Biosynthetic Process MRNA Catabolic Process Transcription Termination Site Sequence-specific DNA Binding RRNA Processing Nuclear-transcribed MRNA Catabolic Process RNA Catabolic Process 5'-3' RNA Exonuclease Activity RRNA Metabolic Process Regulation Of Golgi Lumen Acidification Termination Of RNA Polymerase II Transcription Poly(A)-dependent SnoRNA 3'-end Processing U4 SnRNA 3'-end Processing Nucleobase-containing Compound Catabolic Process 5'-3' Exonuclease Activity Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Nuclear MRNA Surveillance DNA Deamination Nucleolar Exosome (RNase Complex) Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity RRNA Catabolic Process Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Sno(s)RNA Metabolic Process Male Gamete Generation Spermatogenesis DNA-templated Transcription Termination SnRNA 3'-end Processing Gamete Generation Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Multivesicular Body Membrane Positive Regulation Of Isotype Switching Somatic Diversification Of Immunoglobulins Involved In Immune Response DNA Modification 3'-5'-RNA Exonuclease Activity MRNA Metabolic Process Acrosome Assembly Aggresome SnRNA Processing Somatic Recombination Of Immunoglobulin Gene Segments Nuclear RNA Surveillance Regulation Of Isotype Switching RNA Surveillance Positive Regulation Of Immunoglobulin Mediated Immune Response
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