CPAMD8

Gene Name		C3 and PZP-like, alpha-2-macroglobulin domain containing 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Negative Regulation Of Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS		Brain lesion load ( 19010793) Crohn's disease ( 22412388)
Protein-protein Interactions		3 interactors: ADCYAP1 DPP4 SCTR
Entrez ID		27151
HPRD ID		09892
Ensembl ID		ENSG00000160111
Uniprot IDs		Q6NVW5 Q8IZJ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Somatostatin Secretion Negative Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Growth Hormone Secretion Regulation Of Cell-cell Adhesion Mediated By Integrin Regulation Of Oligodendrocyte Progenitor Proliferation Regulation Of Growth Hormone Secretion Negative Regulation Of Glial Cell Proliferation Negative Regulation Of Inflammatory Response To Antigenic Stimulus Negative Regulation Of Rho GTPase Activity Negative Regulation Of Acute Inflammatory Response Histamine Secretion Positive Regulation Of Rap GTPase Activity Histamine Transport Negative Regulation Of Ras GTPase Activity Regulation Of Rap GTPase Activity CAMP-mediated Signaling Negative Regulation Of Potassium Ion Transport Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Rap Protein Signal Transduction Positive Regulation Of Cell Proliferation Activation Of Adenylate Cyclase Activity Cyclic-nucleotide-mediated Signaling Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Vasodilation Negative Regulation Of GTPase Activity Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Adenylate Cyclase Activity Behavioral Fear Response Regulation Of Extracellular Matrix Organization Fear Response Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Vasodilation Excretion Positive Regulation Of Lyase Activity Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Regulation Of Muscle Cell Apoptotic Process Pituitary Gland Development Regulation Of Adenylate Cyclase Activity
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