CPAMD8

Name	C3 and PZP like alpha-2-macroglobulin domain containing 8
Structure	No pdb structure
Interactors	3 interactors: ADCYAP1 DPP4 SCTR
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity
	Biological Process	Eye Development
GWAS	Brain lesion load ( 19010793 ) Cataracts ( 34127677 ) Crohn's disease ( 22412388 ) Height ( 28552196 ) Retinal detachment or retinal break ( 31816047 )
Entrez ID	27151
HPRD ID	09892
Ensembl ID	ENSG00000160111
Uniprot IDs	A0A494C0S9 Q8IZJ3
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Type 2 Vasoactive Intestinal Polypeptide Receptor Binding Type 1 Vasoactive Intestinal Polypeptide Receptor Binding Pituitary Adenylate Cyclase Activating Polypeptide Activity Glucagon Processing Secretin Receptor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Signaling Receptor Binding Peptide Hormone Receptor Binding Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production Positive Regulation Of Growth Hormone Secretion Intercellular Canaliculus Negative Regulation Of Extracellular Matrix Disassembly Adhesion Of Symbiont To Host Cell Receptor-mediated Endocytosis Of Virus By Host Cell Receptor-mediated Virion Attachment To Host Cell Negative Regulation Of Neutrophil Migration Regulation Of Cell-cell Adhesion Mediated By Integrin Negative Regulation Of Neutrophil Chemotaxis Dipeptidyl-peptidase Activity Psychomotor Behavior Virion Attachment To Host Cell Diet Induced Thermogenesis Intracellular Water Homeostasis Regulation Of Growth Hormone Secretion Activation Of Adenylate Cyclase Activity Adhesion Of Symbiont To Host Endocytosis Involved In Viral Entry Into Host Cell Locomotory Exploration Behavior Regulation Of Hormone Levels Positive Regulation Of CAMP/PKA Signal Transduction Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Lyase Activity Regulation Of Biological Quality Positive Regulation Of Cyclase Activity Negative Regulation Of Extracellular Matrix Organization Lamellipodium Membrane Negative Regulation Of Leukocyte Chemotaxis Regulation Of Extracellular Matrix Disassembly Chemorepellent Activity Adaptive Thermogenesis Regulation Of Appetite Motor Behavior Neuropeptide Hormone Activity Aminopeptidase Activity Regulation Of Neutrophil Chemotaxis G Protein-coupled Receptor Signaling Pathway Behavioral Fear Response Exploration Behavior Behavioral Defense Response