FOXD3

Gene Name		forkhead box D3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Trophectodermal Cell Differentiation Embryonic Placenta Development Transcription, DNA-templated Somatic Stem Cell Maintenance Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Transcriptional regulation of pluripotent stem cells POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: POU5F1
Entrez ID		27022
HPRD ID		07018
Ensembl ID		ENSG00000187140
Uniprot IDs		Q9UJU5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Heart Induction By Regulation Of Canonical Wnt Signaling Pathway BMP Signaling Pathway Involved In Heart Induction Negative Regulation Of Gene Silencing By MiRNA Regulation Of Methylation-dependent Chromatin Silencing Cardiac Cell Fate Determination BMP Signaling Pathway Involved In Heart Development Regulation Of Asymmetric Cell Division Endodermal Cell Fate Specification Regulation Of Gene Silencing By MiRNA Positive Regulation Of Catenin Import Into Nucleus MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of SMAD Protein Import Into Nucleus MRNA Transcription Endodermal Cell Fate Commitment Regulation Of SMAD Protein Import Into Nucleus Regulation Of Cell Fate Specification Regulation Of Gene Silencing Regulation Of Catenin Import Into Nucleus Regulation Of Transcription Involved In Cell Fate Commitment Regulation Of Heart Morphogenesis Cell Fate Commitment Involved In Formation Of Primary Germ Layer Regulation Of Cell Fate Commitment Organ Induction Endodermal Cell Differentiation Developmental Induction Regulation Of Organ Formation Cell Fate Determination Endoderm Formation Somatic Stem Cell Maintenance BMP Signaling Pathway Endoderm Development Positive Regulation Of Protein Import Into Nucleus Cell Fate Specification Blastocyst Development Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Formation Of Primary Germ Layer Cardiocyte Differentiation Stem Cell Maintenance Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Organ Morphogenesis Gastrulation Regulation Of Protein Localization To Nucleus Regulation Of Chromosome Organization Regulation Of Nucleocytoplasmic Transport Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Stem Cell Development
Tagcloud ?		abundantly border commences complexity crest dimethylation distinguishing methyltransferase methyltransferases migratory msx1 multipotent neural neurepithelium nevertheless nsd3 plate precursors premigratory requirement revealing snail2 sox10 sox9 spatiotemporally specification stationary temporally unexpected