TPK1

Description		thiamin pyrophosphokinase 1
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Nucleotide Binding Thiamine Diphosphokinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Thiamine Binding Identical Protein Binding UTP Thiamine Diphosphokinase Activity
	Biological Process	Thiamine Metabolic Process Thiamine Diphosphate Biosynthetic Process Regulation Of Pyruvate Decarboxylation To Acetyl-CoA
Pathways		Vitamin B1 (thiamin) metabolism
Drugs		Thiamine Pyrithiamine Pyrophosphate
Diseases
GWAS		Fruit consumption ( 32066663) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Iris color (b* coordinate) ( 30895295) Smoking status (heavy vs never) ( 26423011)
Interacting Genes		1 interacting genes: OPLAH
Entrez ID		27010
HPRD ID		06967
Ensembl ID		ENSG00000196511
Uniprot IDs		A0A090N8Y0 B3KRJ6 F5GZG6 Q6ZQX6 Q9H3S4
PDB IDs		3S4Y 9HJC
Enriched GO Terms of Interacting Partners?		5-oxoprolinase (ATP-hydrolyzing) Activity Glutathione Metabolic Process
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