GHRH

Description		growth hormone releasing hormone
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Terminal Bouton Perikaryon
	Molecular Function	Signaling Receptor Binding Hormone Activity Neuropeptide Hormone Activity Growth Hormone-releasing Hormone Activity Growth Hormone-releasing Hormone Receptor Binding Peptide Hormone Receptor Binding
	Biological Process	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Adenohypophysis Development Growth Hormone Secretion Response To Food Regulation Of Protein Localization Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Circadian Sleep/wake Cycle, REM Sleep Hormone Secretion Positive Regulation Of Hormone Secretion Positive Regulation Of Growth Hormone Secretion Positive Regulation Of CAMP/PKA Signal Transduction
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors
Drugs
Diseases		Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS		Height ( 31562340)
Interacting Genes		2 interacting genes: GHRHR SNCA
Entrez ID		2691
HPRD ID		11752
Ensembl ID		ENSG00000118702
Uniprot IDs		P01286
PDB IDs		5BQM 7CZ5 7V9M
Enriched GO Terms of Interacting Partners?		Nuclear Outer Membrane Signal Release Somatotropin Secreting Cell Development Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Secretion Growth Hormone-releasing Hormone Receptor Activity Positive Regulation Of Secretion By Cell Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Chaperone-mediated Autophagy Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Secretion By Cell Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Growth Hormone Secretion Dopamine Uptake Involved In Synaptic Transmission Secretion CAMP/PKA Signal Transduction Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Adenohypophysis Development Positive Regulation Of Growth Hormone Secretion Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Regulation Of Secretion By Cell Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Secretion Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Regulation Of Growth Hormone Secretion
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