GCHFR

Gene Name		GTP cyclohydrolase I feedback regulator
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Dendrite Nuclear Membrane Melanosome Protein Complex
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Amino Acid Binding GTP-dependent Protein Binding GTP Cyclohydrolase Binding
	Biological Process	Nitric Oxide Biosynthetic Process Negative Regulation Of Biosynthetic Process Neurotransmitter Metabolic Process Negative Regulation Of GTP Cyclohydrolase I Activity Small Molecule Metabolic Process Nitric Oxide Metabolic Process Regulation Of Nitric-oxide Synthase Activity Protein Heterooligomerization
Pathways		Metabolism of nitric oxide eNOS activation and regulation Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: GCH1
Entrez ID		2644
HPRD ID		03895
Ensembl ID		ENSG00000137880
Uniprot IDs		P30047
PDB IDs
Enriched GO Terms of Interacting Partners?		7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Regulation Of Lung Blood Pressure Dihydrobiopterin Metabolic Process Tetrahydrofolate Biosynthetic Process Tetrahydrobiopterin Biosynthetic Process Dopamine Biosynthetic Process Nitric Oxide Biosynthetic Process Neuromuscular Process Controlling Posture Positive Regulation Of Nitric-oxide Synthase Activity Catecholamine Biosynthetic Process Tetrahydrofolate Metabolic Process Positive Regulation Of Monooxygenase Activity Nitric Oxide Metabolic Process Dopamine Metabolic Process Folic Acid-containing Compound Biosynthetic Process Reactive Nitrogen Species Metabolic Process Vasodilation Pteridine-containing Compound Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Oxidoreductase Activity Response To Pain Catecholamine Metabolic Process Folic Acid-containing Compound Metabolic Process Negative Regulation Of Blood Pressure Pteridine-containing Compound Metabolic Process Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Oxidoreductase Activity Multicellular Organismal Response To Stress Phenol-containing Compound Metabolic Process Reactive Oxygen Species Metabolic Process Response To Tumor Necrosis Factor Neuromuscular Process Cellular Amino Acid Biosynthetic Process Protein Heterooligomerization Coenzyme Biosynthetic Process Response To Interferon-gamma Regulation Of Blood Pressure Cellular Modified Amino Acid Metabolic Process Cellular Amide Metabolic Process Protein Homooligomerization Alpha-amino Acid Metabolic Process Blood Circulation Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Cofactor Metabolic Process Protein Oligomerization Cellular Amino Acid Metabolic Process Response To Bacterium Response To Cytokine
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