FBXO6

Gene Name		F-box protein 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm SCF Ubiquitin Ligase Complex
	Molecular Function	Glycoprotein Binding Ubiquitin-protein Transferase Activity Protein Binding Carbohydrate Binding
	Biological Process	DNA Damage Checkpoint DNA Repair Proteolysis Glycoprotein Catabolic Process Response To Unfolded Protein Protein Ubiquitination ER-associated Ubiquitin-dependent Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		Protein folding Antigen processing: Ubiquitination & Proteasome degradation Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: ORC4 SKP1
Entrez ID		26270
HPRD ID		07291
Ensembl ID		ENSG00000116663
Uniprot IDs		Q9NRD1
PDB IDs
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Histone H2A Monoubiquitination Mitotic Cell Cycle Histone H2A Ubiquitination Histone Monoubiquitination Cell Cycle Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process DNA Replication Initiation Histone Ubiquitination Cell Cycle Protein Monoubiquitination Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process DNA-dependent DNA Replication G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Notch Signaling Pathway Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Circadian Rhythm
Tagcloud ?		ablated abolished almost attenuating bip cadmium chop elevation endoplasmic entirely er erad functioning hek293 inhibiting inhibition jnk1 jun ligase markedly precise reticulum sensitivity stress subsequent substrate thereby ubiquitin unexplored