AMD1

Name	adenosylmethionine decarboxylase 1
Structure
Interactors	2 interactors: HSPB1 THAP4
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Adenosylmethionine Decarboxylase Activity Protein Binding Lyase Activity Carboxy-lyase Activity Putrescine Binding Identical Protein Binding
	Biological Process	Polyamine Metabolic Process Polyamine Biosynthetic Process Spermine Biosynthetic Process Spermidine Biosynthetic Process
Pathways	Metabolism of polyamines
Drugs	Ademetionine Putrescine 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine
GWAS	Blood metabolite levels ( 26401656 )
Entrez ID	262
HPRD ID	01622
Ensembl ID	ENSG00000123505
Uniprot IDs	A0A088AWN0 B4DZ60 P17707 Q5VXN5
PDB IDs	1I72 1I79 1I7B 1I7C 1I7M 1JEN 1JL0 1MSV 3DZ2 3DZ3 3DZ4 3DZ5 3DZ6 3DZ7 3EP3 3EP4 3EP5 3EP6 3EP7 3EP8 3EP9 3EPA 3EPB 3H0V 3H0W
GO Terms Enriched among Interactors ?	Negative Regulation Of Protein Kinase C Signaling Peroxynitrite Isomerase Activity Protein Kinase C Inhibitor Activity Nitrate Metabolic Process Regulation Of Protein Kinase C Signaling Nitric Oxide Binding Anterograde Axonal Protein Transport Positive Regulation Of Endothelial Cell Chemotaxis Protein Transport Along Microtubule Contractile Muscle Fiber Tyrosine Metabolic Process Protein Refolding Cellular Response To Vascular Endothelial Growth Factor Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Reactive Nitrogen Species Metabolic Process Aromatic Amino Acid Metabolic Process Protein Localization To Synapse Positive Regulation Of Blood Vessel Endothelial Cell Migration Protein Folding Chaperone Protein Kinase C Binding Platelet Aggregation Axon Cytoplasm Positive Regulation Of Interleukin-1 Beta Production Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Axonal Transport Anterograde Axonal Transport Cornified Envelope Proteasome Complex Homotypic Cell-cell Adhesion Positive Regulation Of Interleukin-1 Production