LRRTM2

Description		leucine rich repeat transmembrane neuronal 2
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane Synapse Postsynaptic Membrane Excitatory Synapse Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse Postsynaptic Specialization Membrane
	Molecular Function	Protein Binding Neurexin Family Protein Binding
	Biological Process	Negative Regulation Of Receptor Internalization Synapse Organization Positive Regulation Of Synapse Assembly Long-term Synaptic Potentiation Regulation Of Postsynaptic Density Assembly
Pathways		Neurexins and neuroligins
Drugs
Diseases
GWAS		Malaria ( 31844061)
Interacting Genes		2 interacting genes: TMEM120B TNF
Entrez ID		26045
HPRD ID		17454
Ensembl ID		ENSG00000146006
Uniprot IDs		O43300
PDB IDs		5Z8X 5Z8Y
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Chronic Inflammatory Response To Antigenic Stimulus Response To Gram-negative Bacterium Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Fractalkine Production Negative Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Positive Regulation Of Vitamin D Biosynthetic Process Response To 3,3',5-triiodo-L-thyronine Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Positive Regulation Of Neutrophil Activation Response To Transition Metal Nanoparticle Positive Regulation Of Synoviocyte Proliferation Positive Regulation Of Chronic Inflammatory Response Regulation Of Bile Acid Secretion Death Receptor Agonist Activity Response To Isolation Stress Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Negative Regulation Of Bicellular Tight Junction Assembly Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Vascular Endothelial Growth Factor Production Positive Regulation Of Fever Generation Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Branching Involved In Salivary Gland Morphogenesis Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of Podosome Assembly Response To Macrophage Colony-stimulating Factor Negative Regulation Of Amyloid-beta Clearance Chronic Inflammatory Response Response To Fructose Endothelial Cell Apoptotic Process Positive Regulation Of Action Potential Regulation Of Neutrophil Activation Necroptotic Signaling Pathway Regulation Of Chronic Inflammatory Response Regulation Of Fever Generation Cellular Response To Nicotine Negative Regulation Of Cellular Respiration Positive Regulation Of Heat Generation Positive Regulation Of Interleukin-18 Production Negative Regulation Of Myelination Negative Regulation Of Vascular Wound Healing Positive Regulation Of Hepatocyte Proliferation Negative Regulation Of Oxidative Phosphorylation
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