CLIC4

Gene Name		chloride intracellular channel 4
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Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Microvillus Cell-cell Junction Cell Surface Actin Cytoskeleton Microtubule Cytoskeleton Nuclear Matrix Midbody Cytoplasmic Vesicle Membrane Chloride Channel Complex Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Angiogenesis Endothelial Cell Morphogenesis Chloride Transport Apoptotic Process Vacuolar Acidification Fertilization Cell Differentiation Keratinocyte Differentiation Negative Regulation Of Cell Migration Regulation Of Ion Transmembrane Transport Establishment Or Maintenance Of Apical/basal Cell Polarity Multicellular Organism Growth Branching Morphogenesis Of An Epithelial Tube Regulation Of Cytoskeleton Organization Retina Vasculature Morphogenesis In Camera-type Eye Cellular Response To Calcium Ion Chloride Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Height ( 20881960)
Protein-protein Interactions		5 interactors: ACTB DNM1 HSP90AB1 REL YWHAZ
Entrez ID		25932
HPRD ID		05943
Ensembl ID		ENSG00000169504
Uniprot IDs		Q6FIC5 Q9Y696
PDB IDs		2AHE 2D2Z 3OQS
Enriched GO Terms of Interacting Partners?		Immune Response Axon Guidance Defense Response Vesicle-mediated Transport Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Ephrin Receptor Signaling Pathway Neuron Projection Morphogenesis Endocytosis Cell Morphogenesis Involved In Differentiation Immune System Process Innate Immune Response Neuron Projection Development Cell Projection Morphogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Part Morphogenesis Signal Transduction Neuron Development Platelet Activation Negative Regulation Of Cell Death Negative Regulation Of Neuron Death Signaling Golgi Reassembly Cell Morphogenesis Cell Communication Positive Regulation Of Intracellular Transport Neuron Differentiation Cell Projection Organization Histamine Secretion By Mast Cell Phagocytosis Fc Receptor Signaling Pathway Establishment Of Golgi Localization Locomotion Immune Response-activating Cell Surface Receptor Signaling Pathway Protein Folding Regulation Of Neuron Death Golgi Inheritance Cellular Response To Stimulus Histamine Secretion Response To Stress Movement Of Cell Or Subcellular Component Immune Response-regulating Cell Surface Receptor Signaling Pathway Histamine Transport Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Cell Death Generation Of Neurons
Tagcloud ?		antagonism antagonists atg5 atg7 attenuate autophagy blockade compromise ct414 decarboxylase fail h1r h2r h3r h3rs hdc histamine histidine ischaemia ischaemic knockout methyladenine neuroprotection protects reinforces reperfusion reversed suppressing tat