SGMS1

Gene Name		sphingomyelin synthase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Trans Cisterna Golgi Membrane Nucleus Endoplasmic Reticulum Plasma Membrane Membrane Integral Component Of Golgi Membrane
	Molecular Function	Kinase Activity Sphingomyelin Synthase Activity Ceramide Cholinephosphotransferase Activity
	Biological Process	Sphingolipid Metabolic Process Sphingomyelin Biosynthetic Process Apoptotic Process Inflammatory Response Positive Regulation Of Gene Expression Cell Growth Phosphorylation Sphingolipid Biosynthetic Process Small Molecule Metabolic Process Cellular Response To Lipopolysaccharide Cellular Response To Tumor Necrosis Factor Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Response to amphetamines ( 22952603)
Protein-protein Interactions		2 interactors: ATXN1 STK4
Entrez ID		259230
HPRD ID		18203
Ensembl ID		ENSG00000198964
Uniprot IDs		D3DWC4 Q86VZ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Primitive Hemopoiesis Tube Development Endocardium Development Hepatocyte Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Signal Transduction Hippo Signaling Negative Regulation Of Signaling Embryonic Hemopoiesis Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Phosphorylation Negative Regulation Of Organ Growth Regulation Of Phosphorus Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Patterning Of Blood Vessels Lung Alveolus Development Positive Regulation Of Fat Cell Differentiation
Tagcloud ?		abeta ad altering amyloid app brains cerebellum contributing generation hallmark hippocampus impacts lipids pathological pathology plaques precursor processing produce proteolysis put secondly sequential sphingomyelin synthase transmenbrane unclear viability