MTHFD1L

Gene Name		methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Membrane
	Molecular Function	Formate-tetrahydrofolate Ligase Activity Methenyltetrahydrofolate Cyclohydrolase Activity Methylenetetrahydrofolate Dehydrogenase (NADP+) Activity ATP Binding Protein Homodimerization Activity
	Biological Process	One-carbon Metabolic Process Folic Acid-containing Compound Metabolic Process Folic Acid-containing Compound Biosynthetic Process Formate Metabolic Process Tetrahydrofolate Interconversion Tetrahydrofolate Metabolic Process Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 20885792) Chronic myeloid leukemia ( 21540461) Coronary heart disease ( 17634449)
Protein-protein Interactions		1 interactors: HGS
Entrez ID		25902
HPRD ID		09967
Ensembl ID		ENSG00000120254
Uniprot IDs		B2RD24 B7ZM99 Q6UB35
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Targeting To Lysosome Protein Localization To Lysosome Membrane Invagination Negative Regulation Of JAK-STAT Cascade Protein Targeting To Vacuole Establishment Of Protein Localization To Vacuole Endosome To Lysosome Transport Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Exocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Regulation Of ERBB Signaling Pathway Regulation Of JAK-STAT Cascade Regulation Of Exocytosis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Endosomal Transport Positive Regulation Of Secretion Establishment Of Protein Localization To Organelle Protein Localization To Membrane Regulation Of Vesicle-mediated Transport Regulation Of Protein Catabolic Process
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