GALR1

Description		galanin receptor 1
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Galanin Receptor Activity Protein Binding Peptide Hormone Binding Neuropeptide Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cortisol Secretion
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		A body shape index ( 34021172) Appendicular lean mass ( 33097823) Blood osmolality (transformed sodium) ( 28360221) DHEAS levels ( 34748635) Height ( 31562340) Metabolite levels ( 31628463) Obesity-related traits ( 23251661) Smoking initiation (ever regular vs never regular) ( 31089300) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Novel Interacting Genes		1 novel interacting genes: CD226
Interacting Genes		2 interacting genes: GAL SNAPC5
Entrez ID		2587
HPRD ID		02657
Ensembl ID		ENSG00000166573
Uniprot IDs		P47211
PDB IDs		7WQ3 7XJJ
Enriched GO Terms of Interacting Partners?		Type 2 Galanin Receptor Binding Type 3 Galanin Receptor Binding Positive Regulation Of Large Conductance Calcium-activated Potassium Channel Activity Type 1 Galanin Receptor Binding Galanin Receptor Binding Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Positive Regulation Of Mast Cell Activation Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Natural Killer Cell Cytokine Production Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Protein Kinase A Signaling Positive Regulation Of Timing Of Catagen Positive Regulation Of Hair Follicle Development Positive Regulation Of Cortisol Secretion Galanin Receptor Activity Regulation Of Glucocorticoid Metabolic Process Regulation Of Timing Of Catagen SnRNA Transcription Parental Behavior Positive Regulation Of Immune Response To Tumor Cell Regulation Of Mast Cell Activation Positive Regulation Of T Cell Receptor Signaling Pathway Regulation Of Hair Follicle Development Regulation Of Cell Activation Response To Immobilization Stress Positive Regulation Of Cation Channel Activity Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Neuropeptide Hormone Activity Regulation Of Hair Cycle Transcription By RNA Polymerase III Reproductive Behavior Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Regulation Of Hormone Metabolic Process Positive Regulation Of Natural Killer Cell Mediated Immunity RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of Immunoglobulin Mediated Immune Response Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Transporter Activity Natural Killer Cell Mediated Immunity Insulin Secretion
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