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ARIH1
Gene Name
ariadne RBR E3 ubiquitin protein ligase 1
Image
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Cytoplasm
Cytosol
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Cytokine-mediated Signaling Pathway
Pathways
ISG15 antiviral mechanism
Interferon Signaling
Cytokine Signaling in Immune system
Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS
Protein-protein Interactions
10 interactors:
CUL1
EIF4E2
NEDD8
PLD1
UBE2D1
UBE2D3
UBE2E2
UBE2L3
UBE2L6
VAV2
Entrez ID
25820
HPRD ID
05730
Ensembl ID
ENSG00000166233
Uniprot IDs
Q9Y4X5
PDB IDs
1WD2
4KBL
4KC9
Enriched GO Terms of Interacting Partners
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Protein Modification By Small Protein Conjugation
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Ubiquitination
Protein Catabolic Process
Protein K11-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
Cellular Response To Organic Substance
ISG15-protein Conjugation
Cellular Response To Stimulus
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Regulation Of Ubiquitin-protein Transferase Activity
Proteolysis
Response To Organic Substance
Positive Regulation Of Protein Ubiquitination
Response To Stimulus
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Protein Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Transferase Activity
Cell Surface Receptor Signaling Pathway
Response To Transforming Growth Factor Beta
Cellular Response To Growth Factor Stimulus
Cellular Protein Modification Process
Regulation Of Protein Ubiquitination
Response To Growth Factor
Defense Response
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Proteasomal Protein Catabolic Process
Negative Regulation Of Type I Interferon Production
Signal Transduction
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Innate Immune Response
Regulation Of DNA-templated Transcription In Response To Stress
Protein Metabolic Process
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Cell Communication
Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud
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ariadne
c3hc4
cadre
conjugating
denoted
e2s
e3
e3s
explaining
fails
hect
hects
hhari
highlighting
hybrids
ibr
ligases
obligate
park2
parkin
rbr
rbrs
ring
ring2
thioester
ub
ubch5
ubch7
ube2l3