SLC39A6

Description		solute carrier family 39 member 6
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Lamellipodium Membrane Cell Projection Membrane Raft
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Metal Ion Transmembrane Transporter Activity Monoatomic Cation:bicarbonate Symporter Activity
	Biological Process	Epithelial To Mesenchymal Transition Monoatomic Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Bicarbonate Transport Metal Ion Transport Intracellular Monoatomic Cation Homeostasis Lymphocyte Activation T Cell Receptor Signaling Pathway Transmembrane Transport Zinc Ion Transmembrane Transport Zinc Ion Import Across Plasma Membrane
Pathways		Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS		Esophageal squamous cell cancer (length of survival) ( 23644492)
Interacting Genes		6 interacting genes: BCL2L2 MTNR1B RETREG3 SLC10A6 SPP1 TMEM31
Entrez ID		25800
HPRD ID		12285
Ensembl ID		ENSG00000141424
Uniprot IDs		Q13433
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Sertoli Cell Proliferation Melatonin Receptor Activity Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Androgen Catabolic Process Cellular Response To Testosterone Stimulus Endoplasmic Reticulum-autophagosome Adaptor Activity Bile Acid:sodium Symporter Activity Response To 2,3,7,8-tetrachlorodibenzodioxine Substrate Localization To Autophagosome Bcl-2 Family Protein Complex Response To Macrophage Colony-stimulating Factor Regulation Of Hormone Secretion Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Positive Regulation Of Bone Resorption Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration
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