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LCORL
Description
ligand dependent nuclear receptor corepressor like
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Molecular Function
DNA Binding
Protein Binding
Histone Methyltransferase Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) (
24025145
)
Alanine aminotransferase levels (
33547301
)
Alzheimer's disease progression score (
29860282
)
Appendicular lean mass (
33097823
)
Birth length (
25281659
)
Birth weight (
27680694
31043758
23202124
)
BMI at 1 year old (
31575865
)
BMI at 1.5 years old (
31575865
)
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Chronotype (
30696823
)
Colorectal cancer (diet interaction) (
24743840
)
Diverticular disease (
30177863
)
Familial squamous cell lung carcinoma (
29924316
)
General risk tolerance (MTAG) (
30643258
)
Hand grip strength (
29691431
)
HDL cholesterol levels (
32203549
)
HDL cholesterol levels in HIV infection (
33109212
)
Heel bone mineral density (
30598549
)
Height (
31562340
33713608
34270706
18391952
18391951
28552196
19343178
20189936
20881960
21998595
28270201
22021425
23563607
25429064
25282103
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Hip circumference adjusted for BMI (
34021172
25673412
)
Infant length (
25281659
)
Offspring birth weight (
31043758
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Refractive error (
32231278
)
Reticulocyte fraction of red cells (
32888494
)
Systolic blood pressure (
30224653
30578418
)
Triglyceride levels (
32203549
)
Type 2 diabetes (
30297969
)
Waist circumference adjusted for BMI (adjusted for smoking behaviour) (
28443625
)
Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) (
28443625
)
Waist circumference adjusted for BMI in non-smokers (
28443625
)
Waist circumference adjusted for BMI in smokers (
28443625
)
Waist circumference adjusted for body mass index (
25673412
34021172
28552196
)
Weight (
28552196
)
Youthful appearance (self-reported) (
32339537
)
Interacting Genes
3 interacting genes:
CTBP2
MAGEA6
MIR206
Entrez ID
254251
HPRD ID
10088
Ensembl ID
ENSG00000178177
Uniprot IDs
A0A1B0GVP4
A0A6Q8PHE0
A0A6Q8PHT2
B4DSW0
Q8N3X6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription Repressor Complex
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Regulation Of Nucleobase-containing Compound Metabolic Process
White Fat Cell Differentiation
Viral Genome Replication
Transcription Coregulator Binding
Regulation Of Retinoic Acid Receptor Signaling Pathway
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of RNA Metabolic Process
NAD Binding
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Negative Regulation Of Metabolic Process
Transcription Corepressor Binding
Positive Regulation Of Myotube Differentiation
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Neuroinflammatory Response
Regulation Of Amyloid Precursor Protein Catabolic Process
Positive Regulation Of Amyloid-beta Formation
Negative Regulation Of Interleukin-6 Production
Regulation Of Myotube Differentiation
Positive Regulation Of Cholesterol Efflux
Negative Regulation Of Cell Adhesion Molecule Production
Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Lipid Biosynthetic Process
MRNA Base-pairing Post-transcriptional Repressor Activity
Negative Regulation Of Cholesterol Efflux
Regulation Of Amyloid-beta Formation
Negative Regulation Of Lipid Transport
Regulation Of Cholesterol Transport
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Cell Fate Commitment
Regulation Of Cell Fate Commitment
Negative Regulation Of Blood Vessel Endothelial Cell Migration
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of Cholesterol Efflux
Positive Regulation Of Striated Muscle Cell Differentiation
Regulation Of Neuroinflammatory Response
Negative Regulation Of Cholesterol Transport
Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Amide Metabolic Process
Regulation Of Cell Adhesion Molecule Production
Positive Regulation Of Cholesterol Transport
Positive Regulation Of Interleukin-1 Production
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Muscle Cell Differentiation
Regulation Of Amide Metabolic Process
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