IL27

Gene Name		interleukin 27
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space
	Molecular Function	Receptor Binding Cytokine Activity Interleukin-27 Receptor Binding
	Biological Process	Inflammatory Response Response To Bacterium Regulation Of T Cell Proliferation Positive Regulation Of Interferon-gamma Biosynthetic Process Innate Immune Response Regulation Of T-helper 1 Cell Differentiation Regulation Of Defense Response To Virus
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Inflammatory bowel disease (early onset) ( 19915574) Type 1 diabetes ( 19430480) Type 1 diabetes autoantibodies ( 21829393)
Protein-protein Interactions		1 interactors: IL27RA
Entrez ID		246778
HPRD ID		16307
Ensembl ID		ENSG00000197272
Uniprot IDs		Q8NEV9
PDB IDs
Enriched GO Terms of Interacting Partners?		Interleukin-27-mediated Signaling Pathway Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of T-helper 1 Type Immune Response Negative Regulation Of Type 2 Immune Response Regulation Of Isotype Switching Regulation Of Type 2 Immune Response Positive Regulation Of Interferon-gamma Production Defense Response To Gram-positive Bacterium Regulation Of DNA Recombination Regulation Of Interferon-gamma Production Negative Regulation Of Immune Response Positive Regulation Of Adaptive Immune Response Defense Response To Bacterium Regulation Of Adaptive Immune Response Positive Regulation Of Cytokine Production Negative Regulation Of Immune System Process Regulation Of Lymphocyte Activation Cytokine-mediated Signaling Pathway Regulation Of Cell Activation Response To Bacterium Regulation Of Cytokine Production Cellular Response To Cytokine Stimulus
Tagcloud ?		antiviral candidates chemokines defense delineates derives genetics hairpin herpes hsv identifies ifns immunity infectivity irf3 loci predisposed proinflammatory raw screen shrnas simplex synergistically t1d tagap throughput transduced unbiased uncharacterized