DEFB124

Description		defensin beta 124
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Protein Binding
	Biological Process	Defense Response Canonical NF-kappaB Signal Transduction Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-6 Production Defense Response To Bacterium Innate Immune Response Cellular Response To Peptidoglycan Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways		Beta defensins Defensins
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: NCK2 PGRMC1
Entrez ID		245937
HPRD ID		18759
Ensembl ID		ENSG00000180383
Uniprot IDs		Q8NES8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Signal Complex Assembly Regulation Of Translation In Response To Endoplasmic Reticulum Stress Cytoskeletal Anchor Activity Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Immunological Synapse Formation Negative Regulation Of PERK-mediated Unfolded Protein Response Dendritic Spine Development Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Translation In Response To Stress Regulation Of Translational Initiation In Response To Stress Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Translation In Response To Stress Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Lipoprotein Transport Negative Regulation Of Synapse Organization Smooth Endoplasmic Reticulum Membrane Heme Biosynthetic Process Modification Of Synaptic Structure Synapse Tetrapyrrole Biosynthetic Process Porphyrin-containing Compound Biosynthetic Process Steroid Binding Signaling Receptor Complex Adaptor Activity Lamellipodium Assembly Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Cell Projection Organization Vesicle Membrane Heme Metabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Porphyrin-containing Compound Metabolic Process Lamellipodium Organization Phosphotyrosine Residue Binding Positive Regulation Of Actin Filament Polymerization Ephrin Receptor Signaling Pathway Negative Regulation Of Response To Endoplasmic Reticulum Stress Tetrapyrrole Metabolic Process Cell-cell Recognition Pigment Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Receptor Tyrosine Kinase Binding Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Scaffold Protein Binding ERBB Signaling Pathway Signaling Adaptor Activity Positive Regulation Of Protein Localization To Cell Periphery
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