FOLH1

Gene Name		folate hydrolase (prostate-specific membrane antigen) 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Carboxypeptidase Activity Peptidase Activity Metallopeptidase Activity Dipeptidase Activity Metal Ion Binding
	Biological Process	Proteolysis Folic Acid-containing Compound Metabolic Process
Pathways
Drugs		Capromab L-Glutamic Acid (2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid
Diseases
GWAS		HDL cholesterol ( 19060911) Height ( 20881960)
Protein-protein Interactions		2 interactors: MTAP RPS3
Entrez ID		2346
HPRD ID		02961
Ensembl ID		ENSG00000086205
Uniprot IDs		Q04609
PDB IDs		1Z8L 2C6C 2C6G 2C6P 2CIJ 2JBJ 2JBK 2OOT 2OR4 2PVV 2PVW 2XEF 2XEG 2XEI 2XEJ 3BHX 3BI0 3BI1 3BXM 3D7D 3D7F 3D7G 3D7H 3IWW 3RBU 3SJE 3SJF 3SJG 3SJX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA N-glycosylase Activity Purine Ribonucleoside Salvage Negative Regulation Of DNA Repair L-methionine Biosynthetic Process From Methylthioadenosine L-methionine Salvage Cytoplasmic Translation Methionine Biosynthetic Process Methionine Metabolic Process Sulfur Amino Acid Biosynthetic Process Purine-containing Compound Salvage Polyamine Metabolic Process Response To Testosterone Sulfur Amino Acid Metabolic Process Regulation Of DNA Repair
Tagcloud ?		adam adam17 basing cav1 cav2 cdc42 coexpressed dusp dusp6 fgfr3 flt4 her3 kdr krt18 krt8 lck macroglobulin mmp9 neoangiogenesis pdgfb psm ptk ptp ptpns1 ptprs top2 top2a vav1 vim