SIK3

Description		SIK family kinase 3
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GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Tau-protein Kinase Activity Protein Serine Kinase Activity
	Biological Process	Microtubule Cytoskeleton Organization Protein Phosphorylation Intracellular Signal Transduction Positive Regulation Of TORC1 Signaling Positive Regulation Of TORC2 Signaling
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Allergic rhinitis ( 30013184) Apolipoprotein B levels ( 32203549) Body mass index ( 31978080) Cholesterol ( 31902109) Delirium ( 29631748) Eosinophil count ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) HDL cholesterol ( 24886709 31170924) HDL cholesterol levels ( 32203549) HDL levels x fish oil supplementation interaction (2df) ( 33760818) Hearing function ( 25060954) Mean platelet volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Metabolic syndrome ( 30382898) Non-accommodative esotropia ( 30098192) Platelet count ( 32888494) Red cell distribution width ( 32888494) Refractive error ( 32231278) Response to Vitamin E supplementation ( 22437554) Sum eosinophil basophil counts ( 27863252) Triglyceride levels ( 29615537 32203549) Triglyceride levels x fish oil supplementation interaction (2df) ( 33760818) Triglycerides ( 24886709)
Novel Interacting Genes		1 novel interacting genes: ATP5MG
Interacting Genes		6 interacting genes: CRTC2 HDAC5 PRKACA TRAF1 TRIP6 YWHAZ
Entrez ID		23387
HPRD ID		11121
Ensembl ID		ENSG00000160584
Uniprot IDs		H0Y4E8 Q9Y2K2
PDB IDs		8OKU 8R4O 8R4Q 8R4U 8R4V
Enriched GO Terms of Interacting Partners?
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